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| Tuesday, November 8th , 2022 |
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| New Rochelle Purple Wave: Signed Manager Zach Freeman. |
| Tuesday, November 1st , 2022 |
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| Orono Oaks: LF Mitch Philipp retired from professional baseball. |
| Chesapeake Tailgators: 1B Brent Tilley retired from professional baseball. |
| Laredo Ghosts: Pitching Coach Jeff Poirot retires. |
| Nashville Lasers: Hitting Coach Zach Freeman leaves the team, his contract was not renewed |
| Nashville Lasers: Pitching Coach Will Berman leaves the team, his contract was not renewed |
| Montreal Canadiens: Pitching Coach Cody Yaremko leaves the team, his contract was not renewed |
| Dillonvale Indians: Hitting Coach Kevin Violette leaves the team, his contract was not renewed |
| Ann Arbor Z's: Hitting Coach Bill Ryan leaves the team, his contract was not renewed |
| Ann Arbor Z's: Pitching Coach Matt Beard leaves the team, his contract was not renewed |
| Portland Mad Ants: Pitching Coach Josh Woodson leaves the team, his contract was not renewed |
| Portland Mad Ants: Manager Efren Nieman leaves the team, his contract was not renewed |
| Portland Mad Ants: Hitting Coach Dave Van Natta leaves the team, his contract was not renewed |
| Chesapeake Tailgators: Hitting Coach Bobby Mejia leaves the team, his contract was not renewed |
| Randolph Prairie Thunder: Manager Michael Kelleher leaves the team, his contract was not renewed |
| Randolph Prairie Thunder: Pitching Coach Ricky Calderon leaves the team, his contract was not renewed |
| Monday, October 31st , 2022 |
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| Walnut Park Bobcats: Signed Pitching Coach Ricardo Manzanares to a 2-year contract extension. |
| Wednesday, October 19th , 2022 |
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| Tucson Raccoons: 1B Jeff Kerner retired from professional baseball. |
| Hartford Matadors: SP Jeff Mitchell retired from professional baseball. |
| Glendale Muskies: 1B Bronson Demo retired from professional baseball. |
| Lubbock Stampede: C Edwin Jimenez retired from professional baseball. |
| Fremont Marshalls: SP Alessio Monti retired from professional baseball. |
| Montreal Canadiens: 1B Xavier Crockrell retired from professional baseball. |
| Hickory Crawdads: SP Luis Maldonado retired from professional baseball. |
| Hickory Crawdads: LF Adam Nance retired from professional baseball. |
| Montreal Royals: SP Jonathan Higginbotham retired from professional baseball. |
| Spokane Selects: SP Jeff Rochefort retired from professional baseball. |
| Spokane Selects: C Daniel Covarrubias retired from professional baseball. |
| Denver Pilots: C Mike Blankenship retired from professional baseball. |
| Spokane Selects: 3B Fernando Serrano retired from professional baseball. |
| Lubbock Stampede: SP Jonathan Glover retired from professional baseball. |
| Randolph Prairie Thunder: RP Joel Clark retired from professional baseball. |
| Montreal Royals: RP Andy Baker retired from professional baseball. |
| Montreal Canadiens: RP Chris Brown retired from professional baseball. |
| Montreal Canadiens: RP Robby Harroun retired from professional baseball. |
| New Rochelle Purple Wave: RP Landon Gross retired from professional baseball. |
| Portland Mad Ants: RP Corey Hell retired from professional baseball. |
| Ann Arbor Z's: SP Nate Stout retired from professional baseball. |
| Hickory Crawdads: RP Rob Viviano retired from professional baseball. |
| Portland Mad Ants: RP Cesar Aguirre retired from professional baseball. |
| Walnut Park Bobcats: SP Earl Gomez retired from professional baseball. |
| Nashville Lasers: RP Travis Crane retired from professional baseball. |
| Little Rock Governors: 1B Josh Forbes retired from professional baseball. |
| Quebec Aces: SP Manny Hernandez retired from professional baseball. |
| Montreal Canadiens: RP Adam Wright retired from professional baseball. |
| Chesapeake Tailgators: SP Jeff Tracy retired from professional baseball. |
| Hickory Crawdads: RP Brandon Watts retired from professional baseball. |
| Tucson Raccoons: 3B Bob Adkins retired from professional baseball. |
| Fremont Marshalls: RP Aaron Ewing retired from professional baseball. |
| Lubbock Stampede: RP Miguel Aguirre retired from professional baseball. |
| Quebec Fighting Quakers: 3B Victor Ramirez retired from professional baseball. |
| Tucson Raccoons: SP Oscar Hernandez retired from professional baseball. |
| Denver Pilots: 3B Craig Carter retired from professional baseball. |
| Glendale Muskies: RF Alan Wieben retired from professional baseball. |
| Tucson Raccoons: RP Joe Reddick retired from professional baseball. |
| Denver Pilots: LF Gary Furlow retired from professional baseball. |
| Lubbock Stampede: C Nick Wood retired from professional baseball. |
| Lubbock Stampede: SP Mike Maschke retired from professional baseball. |
| Walnut Park Bobcats: RP Keith Bader retired from professional baseball. |
| Laredo Ghosts: 1B Ryan Perry retired from professional baseball. |
| Orono Oaks: SS Jeremy Wilber retired from professional baseball. |
| Lubbock Stampede: SP Tim Covert retired from professional baseball. |
| Montreal Royals: CL Yeong-ha Kym retired from professional baseball. |
| Quebec Aces: RP Eric Miley retired from professional baseball. |
| Hartford Matadors: Pitching Coach Sean Sterrett retires. |
| Wednesday, September 28th , 2022 |
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| Walnut Park Bobcats: Placed SS Jeff Pulido on the active roster. |
| Tuesday, September 27th , 2022 |
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| Spokane Selects: SP Travis Thurber was designated for assignment. |
| Saturday, September 17th , 2022 |
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| Spokane Selects: CF Jose Figueroa was designated for assignment. |
| Wednesday, September 14th , 2022 |
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| Walnut Park Bobcats: Placed SS Jeff Pulido on the 7-day injured list, retroactive to 09/12/2022. |
| Friday, August 26th , 2022 |
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| Hickory Crawdads: RP Josh Kuhn was designated for assignment. |
| Wednesday, August 24th , 2022 |
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| Denver Pilots: 1B Joe Handler was designated for assignment. |
| Tuesday, August 16th , 2022 |
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| Spokane Selects: RF Danny Aleman was designated for assignment. |
| Saturday, August 13th , 2022 |
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| Walnut Park Bobcats: Placed CL Lee Maher on the active roster. |
| Walnut Park Bobcats: Placed LF Billy Sawyer on the active roster. |
| Thursday, August 4th , 2022 |
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| Hickory Crawdads: RP Victor Figueroa was designated for assignment. |
| Sunday, July 31st , 2022 |
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| Orono Oaks: Placed SP Ryan Henry on the active roster. |
| Orono Oaks: Released C Jason Herrera. |
| Tuesday, July 19th , 2022 |
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| Little Rock Governors: RP Malik Aldridge was designated for assignment. |
| Friday, July 15th , 2022 |
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| New Rochelle Purple Wave: RP Damani Anderson was designated for assignment. |
| Sunday, July 10th , 2022 |
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| Walnut Park Bobcats: Placed CL Lee Maher on the 7-day injured list, retroactive to 07/07/2022. |
| Wednesday, June 29th , 2022 |
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| Spokane Selects: SP Aaron Daniels was designated for assignment. |
| Tuesday, June 28th , 2022 |
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| Orono Oaks: Placed RP Mike Poussard on the active roster. |
| Orono Oaks: Placed SP Ryan Henry on the 7-day injured list, retroactive to 06/25/2022. |
| Saturday, June 25th , 2022 |
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| Portland Mad Ants: SP Bill Rauch was designated for assignment. |
| Spokane Selects: SP Paul Mitchell was designated for assignment. |
| Friday, June 17th , 2022 |
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| Little Rock Governors: SP Mel Duran was designated for assignment. |
| Wednesday, June 8th , 2022 |
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| Walnut Park Bobcats: Placed SP Jason Seymour on the active roster. |
| Walnut Park Bobcats: Released LF Richard Childs. |
| Walnut Park Bobcats: Released SP Charlie Thoemke. |
| Monday, May 30th , 2022 |
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| Spokane Selects: CF Jose Figueroa was designated for assignment. |
| Saturday, May 28th , 2022 |
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| Spokane Selects: SP Jerry Bowman was designated for assignment. |
| Thursday, May 26th , 2022 |
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| Laredo Ghosts: CF Kasey Miller was designated for assignment. |
| Monday, May 23rd , 2022 |
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| Walnut Park Bobcats: Placed SP Jason Seymour on the 7-day injured list, retroactive to 05/20/2022. |
| Saturday, May 14th , 2022 |
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| Little Rock Governors: SS Bill Dennis was designated for assignment. |
| Tuesday, May 10th , 2022 |
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| Spokane Selects: 1B Frank Fernandez was designated for assignment. |
| Tuesday, May 3rd , 2022 |
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| Walnut Park Bobcats: Placed RP Bobby Fawbush on the active roster. |
| Friday, April 1st , 2022 |
|---|
| Walnut Park Bobcats: Placed RP Bobby Fawbush on the 7-day injured list, retroactive to 03/29/2022. |
| Walnut Park Bobcats: Placed LF Billy Sawyer on the 7-day injured list, retroactive to 03/29/2022. |
