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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Julio Negron# | 34 | 2021 | |
| 2 | Jeff Wise# | 26 | 2021 | |
| 3 | Matt Booth# | 22 | 2021 | |
| 4 | Mitch Jarka# | 21 | 2021 | |
| 5 | Danny Emery# | 20 | 2021 | |
| 6 | Mark Riley# | 15 | 2021 | |
| 6 | Pedro Rangel# | 15 | 2021 | |
| 8 | Skyler Swan# | 13 | 2021 | |
| 9 | Pat Kirchner# | 12 | 2021 | |
| 10 | Darren Errigo# | 10 | 2021 | |
| 11 | Jeremy Comey# | 9 | 2021 | |
| 11 | Danny Brusseau# | 9 | 2021 | |
| 13 | Austin Bonneau# | 8 | 2021 | |
| 13 | Matthew Hodges# | 8 | 2021 | |
| 13 | Raul Arreola# | 8 | 2021 | |
| 16 | Isaiah Mill# | 6 | 2021 | |
| 16 | Marty Williams# | 6 | 2021 | |
| 16 | Tyler Lake# | 6 | 2021 | |
| 19 | T.J. Parker# | 5 | 2021 | |
| 20 | Colt Hickenbottom# | 4 | 2021 | |
| 20 | Sean Vernon# | 4 | 2021 | |
| 22 | Ryan Barker# | 3 | 2021 | |
| 23 | Chris Medders# | 1 | 2021 | |
| 24 | Kyle Wiedmeyer# | 0 | 2021 |
