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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Bryan Reining | 194 | 2011-2017 | |
| 2 | Matt Beard | 170 | 2000-2013 | |
| 3 | Justin Messer | 159 | 2000-2012 | |
| 3 | Will Moore | 159 | 2000-2009 | |
| 5 | Jim Patrick | 155 | 2000-2011 | |
| 6 | Jonathan McMahon | 154 | 2001-2009 | |
| 7 | Ian Starcher | 153 | 2000-2012 | |
| 8 | Chris Auger | 148 | 2000-2009 | |
| 9 | Jose Estrada | 146 | 2000-2010 | |
| 10 | Nelson Martinez# | 145 | 2011-2023 | |
| 11 | Jonathan Lung | 142 | 2000-2011 | |
| 12 | Gerardo Lozano | 141 | 2014-2021 | |
| 13 | Dan Hagen | 139 | 2002-2013 | |
| 14 | Jeremy Excell | 137 | 2000-2012 | |
| 14 | Justin Steach | 137 | 2004-2014 | |
| 16 | Andy McCullough | 136 | 2000-2014 | |
| 17 | Chris Marquis | 135 | 2018-2025 | |
| 18 | Ryan Hester | 133 | 2001-2011 | |
| 19 | Mike Henken | 131 | 2001-2011 | |
| 19 | Jonathan Parker | 131 | 2011-2022 | |
| 19 | Morgan Thompson | 131 | 2005-2014 | |
| 22 | Bruce Hernandez | 129 | 2000-2008 | |
| 22 | Fred Muse | 129 | 2000-2012 | |
| 24 | Don Sheffield | 128 | 2000-2011 | |
| 25 | Sean Prevost | 126 | 2005-2014 | |
| 26 | Bill Kilmer | 125 | 2000-2006 | |
| 27 | Josh Adams | 123 | 2000-2014 | |
| 27 | Brad Parish | 123 | 2000-2008 | |
| 29 | Logan Johns | 122 | 2002-2011 | |
| 29 | Matt Taub | 122 | 2005-2016 | |
| 31 | Chris Govier | 120 | 2012-2019 | |
| 32 | Santiago Rodas | 119 | 2000-2010 | |
| 33 | Alan Sweet | 118 | 2000-2009 | |
| 34 | Ken Bixby# | 117 | 2017-2023 | |
| 35 | Markus Mensink | 114 | 2000-2008 | |
| 35 | Mario Munoz | 114 | 2000-2011 | |
| 37 | Carlos Cancio | 113 | 2004-2011 | |
| 37 | Kyle Connell# | 113 | 2015-2026 | |
| 37 | Jose Flores | 113 | 2001-2012 | |
| 37 | Matt McPeak | 113 | 2000-2006 | |
| 41 | Josh Bass# | 112 | 2014-2026 | |
| 41 | Brian Zubia | 112 | 2008-2015 | |
| 43 | Tyler Byrd | 111 | 2000-2011 | |
| 43 | Matt Garcia | 111 | 2004-2013 | |
| 43 | Jonathan Pimentel | 111 | 2000-2011 | |
| 46 | Brian Gann | 110 | 2000-2013 | |
| 46 | Dave Vilca | 110 | 2000-2007 | |
| 48 | Luis Alcoser | 108 | 2005-2022 | |
| 48 | Nate Briceno# | 108 | 2014-2026 | |
| 48 | Ricardo Cortez | 108 | 2005-2012 | |
| 48 | Andrew Severson | 108 | 2016-2021 | |
| 52 | Jon Caruso | 107 | 2004-2013 | |
| 53 | Alfonso Colon | 105 | 2000-2009 | |
| 54 | Roberto Urias | 104 | 2000-2009 | |
| 55 | Andy Firkins | 103 | 2015-2021 | |
| 55 | Sam Godsey | 103 | 2016-2022 | |
| 55 | Tom Parks | 103 | 2013-2016 | |
| 58 | Sean Cofield | 102 | 2011-2021 | |
| 58 | Tadanori Kawasaki | 102 | 2005-2014 | |
| 60 | Ian Harned | 101 | 2000-2010 | |
| 60 | Mike Orlando | 101 | 2000-2008 | |
| 62 | Adam Arnett | 100 | 2000-2009 | |
| 62 | Cameron Brown | 100 | 2011-2018 | |
| 62 | Edgar Gonzalez | 100 | 2000-2009 | |
| 62 | Mario Pellot | 100 | 2000-2011 | |
| 66 | Danny Lopez | 99 | 2000-2011 | |
| 66 | Jake Rogers | 99 | 2014-2019 | |
| 68 | Brian Ballengee | 98 | 2016-2021 | |
| 68 | Russ Daley | 98 | 2005-2013 | |
| 68 | Travis Titus | 98 | 2000-2008 | |
| 68 | Chris Wyzard# | 98 | 2021-2026 | |
| 72 | Dave Gutierrez | 97 | 2001-2007 | |
| 72 | Andy Jackson | 97 | 2005-2013 | |
| 74 | Mike Arnerich# | 96 | 2014-2026 | |
| 74 | Marcos Sanchez | 96 | 2000-2010 | |
| 76 | Carlos Aquino | 95 | 2000-2008 | |
| 76 | Eddie Arriaga | 95 | 2018-2022 | |
| 76 | Paul Herzog | 95 | 2014-2022 | |
| 76 | Paul Reining | 95 | 2013-2022 | |
| 76 | John Woodburn | 95 | 2015-2017 | |
| 81 | Justin Baker# | 93 | 2015-2026 | |
| 81 | Robert Bell | 93 | 2005-2016 | |
| 81 | Cameron Outlaw# | 93 | 2015-2025 | |
| 81 | Marco Vega | 93 | 2006-2017 | |
| 81 | Hyun-jung Whang | 93 | 2004-2010 | |
| 86 | Terry Droubay# | 92 | 2017-2026 | |
| 86 | Arturo Jimenez | 92 | 2003-2013 | |
| 86 | Ramon Sandoval | 92 | 2000-2009 | |
| 86 | Dan Wenger | 92 | 2018-2021 | |
| 90 | Miguel Calamaco | 91 | 2010-2015 | |
| 90 | Chris Pickens | 91 | 2005-2013 | |
| 92 | Roy Doub# | 90 | 2016-2026 | |
| 92 | Nick Kline | 90 | 2007-2023 | |
| 92 | Jesus Quintero | 90 | 2000-2009 | |
| 95 | Daniel Bromley | 89 | 2000-2009 | |
| 95 | Seth Bruno | 89 | 2004-2013 | |
| 95 | Curtis Gring# | 89 | 2019-2022 | |
| 95 | Aaron Harrison | 89 | 2000-2010 | |
| 95 | Jeremy Overton | 89 | 2007-2015 | |
| 100 | Adam Obermeier# | 88 | 2023-2025 |
