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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Jonathan Ashley# | 26 | 2004-2021 | |
| 2 | Yasuzo Yamaoka | 25 | 2005-2019 | |
| 3 | Austin Compton# | 21 | 2015-2021 | |
| 4 | Ramon Hernandez | 20 | 2002-2014 | |
| 4 | Dan Rodriguez | 20 | 2001-2013 | |
| 6 | Jonathan Ellis# | 19 | 2009-2021 | |
| 6 | Michael Mendez# | 19 | 2007-2020 | |
| 6 | Leo Serna# | 19 | 2014-2021 | |
| 9 | Paul Pittman# | 18 | 2013-2021 | |
| 10 | Mitsuaki Sakaguchi | 17 | 2008-2016 | |
| 10 | Pablo Vegas* | 17 | 2000-2012 | |
| 12 | Luis Soto | 16 | 2005-2017 | |
| 13 | Bob Johnson | 15 | 2000-2012 | |
| 13 | Carlos Martinez | 15 | 2003-2016 | |
| 15 | Eric Druin# | 13 | 2011-2021 | |
| 15 | Jason Moore# | 13 | 2017-2021 | |
| 17 | Emilio Abreu# | 12 | 2012-2021 | |
| 17 | John Karpf# | 12 | 2004-2021 | |
| 17 | Billy Porter# | 12 | 2011-2021 | |
| 17 | Chris Wolf | 12 | 2000-2016 | |
| 21 | Mike Barriga | 11 | 2000-2010 | |
| 21 | Jonathan Cabrera# | 11 | 2008-2021 | |
| 21 | Jeff Coleman# | 11 | 2015-2021 | |
| 21 | Brian LaFever | 11 | 2003-2018 | |
| 21 | Johnny Ortega | 11 | 2000-2016 | |
| 21 | Jason Wilson | 11 | 2000-2016 | |
| 27 | Chris Beasley# | 10 | 2016-2021 | |
| 27 | Carlos Escalera* | 10 | 2000-2008 | |
| 27 | Victor Gonzalez# | 10 | 2010-2021 | |
| 27 | Tyler Jordan# | 10 | 2011-2021 | |
| 27 | Jacob Kennedy# | 10 | 2014-2021 | |
| 32 | Emmanuel Haigler | 9 | 2003-2018 | |
| 32 | Joel Harrison | 9 | 2001-2017 | |
| 32 | Rocky Hawke# | 9 | 2018-2021 | |
| 32 | Tony Ochoa# | 9 | 2012-2021 | |
| 32 | Leo Orozco# | 9 | 2016-2021 | |
| 32 | Nick Pratt# | 9 | 2014-2021 | |
| 32 | Bruce Richards# | 9 | 2019-2021 | |
| 32 | Zach Swint | 9 | 2001-2016 | |
| 32 | Josh Terrien# | 9 | 2017-2021 | |
| 32 | Dustin Williams | 9 | 2005-2015 | |
| 42 | Jason Brown# | 8 | 2007-2020 | |
| 42 | Danny Cruz | 8 | 2000-2011 | |
| 42 | Andre Cunningham | 8 | 2008-2019 | |
| 42 | Aaron Kay | 8 | 2000-2013 | |
| 42 | Julio Rojo | 8 | 2000-2008 | |
| 47 | Brett Byrnes | 7 | 2001-2016 | |
| 47 | Barry Evans | 7 | 2000-2007 | |
| 47 | Matthew Little# | 7 | 2018-2021 | |
| 47 | Robby Londono | 7 | 2008-2015 | |
| 47 | Rich Noble | 7 | 2000-2011 | |
| 47 | Mike Plocher | 7 | 2000-2009 | |
| 47 | George Reed | 7 | 2000-2011 | |
| 47 | Fernando Rodriguez | 7 | 2007-2018 | |
| 47 | Rogelio Sanchez | 7 | 2001-2016 | |
| 47 | Danny Solis# | 7 | 2008-2019 | |
| 57 | Steve Ausman | 6 | 2008-2019 | |
| 57 | Chris Bryan# | 6 | 2007-2021 | |
| 57 | Matt Couse | 6 | 2000-2003 | |
| 57 | Justin Cox# | 6 | 2019-2020 | |
| 57 | Kevin Galovich | 6 | 2004-2015 | |
| 57 | Mike Melin# | 6 | 2015-2020 | |
| 57 | Luis Pompa# | 6 | 2012-2019 | |
| 57 | Ernesto Ramirez# | 6 | 2017-2021 | |
| 57 | Steve Reid | 6 | 2000-2008 | |
| 57 | Severo Salcido# | 6 | 2013-2021 | |
| 57 | Caleb Strouse | 6 | 2000-2014 | |
| 57 | Gong-sun Thum# | 6 | 2011-2020 | |
| 57 | Luis Vasquez | 6 | 2006-2016 | |
| 57 | Corey Young# | 6 | 2010-2021 | |
| 57 | Adam Ziarnik | 6 | 2000-2004 | |
| 72 | Joe Albury | 5 | 2011-2015 | |
| 72 | J.P. Arnemann | 5 | 2000-2013 | |
| 72 | Nate Bacle# | 5 | 2015-2020 | |
| 72 | Luciano Camossa | 5 | 2000-2015 | |
| 72 | Alex Chavez# | 5 | 2006-2021 | |
| 72 | Armando Cisneros | 5 | 2000-2012 | |
| 72 | Chris del Castillo | 5 | 2011-2018 | |
| 72 | Jose Figueroa# | 5 | 2011-2021 | |
| 72 | Willie Granados | 5 | 2000-2010 | |
| 72 | Logan Greening | 5 | 2001-2014 | |
| 72 | Joe Handler# | 5 | 2015-2021 | |
| 72 | Aaron Jackson# | 5 | 2016-2021 | |
| 72 | Brian Klomp# | 5 | 2003-2019 | |
| 72 | Johnny McCoskey | 5 | 2000-2011 | |
| 72 | Jon Miller# | 5 | 2015-2019 | |
| 72 | Alberto Ojeda | 5 | 2002-2016 | |
| 72 | David Phelps# | 5 | 2006-2020 | |
| 72 | Israel Salazar | 5 | 2004-2016 | |
| 72 | Jason Savage | 5 | 2010-2019 | |
| 72 | Mike Townsend# | 5 | 2018-2021 | |
| 72 | Dan Walker | 5 | 2001-2015 | |
| 93 | Rodolfo Alvarez | 4 | 2000-2008 | |
| 93 | Marcos Amador# | 4 | 2010-2019 | |
| 93 | Joaquin Bermudez | 4 | 2009-2018 | |
| 93 | Eric Brewer# | 4 | 2015-2021 | |
| 93 | Jacob Coats# | 4 | 2017-2019 | |
| 93 | Dave DeSanto# | 4 | 2017-2020 | |
| 93 | David Diaz# | 4 | 2006-2017 | |
| 93 | Kevin Dorow# | 4 | 2018-2021 |
