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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Jesus Irizarry | 329 | 2005-2016 | |
| 2 | Jeremy Yamakawa* | 293 | 2005-2020 | |
| 3 | Danny Solis | 276 | 2008-2019 | |
| 4 | Jonathan Ashley | 263 | 2004-2021 | |
| 5 | Emmanuel Haigler | 249 | 2003-2018 | |
| 6 | Pablo Vegas* | 237 | 2000-2012 | |
| 7 | Miles Hayes | 234 | 2000-2012 | |
| 8 | Manuel Rosas# | 215 | 2021-2026 | |
| 9 | George Reed | 204 | 2000-2011 | |
| 10 | Rich Noble | 203 | 2000-2011 | |
| 11 | Jeff Coleman# | 197 | 2015-2024 | |
| 12 | Gary Dineen | 172 | 2000-2016 | |
| 13 | Brett Byrnes* | 171 | 2001-2016 | |
| 13 | Shane Jenkins | 171 | 2000-2013 | |
| 15 | Tony Ochoa | 167 | 2012-2024 | |
| 16 | Gabriel Perez | 145 | 2006-2018 | |
| 17 | Aaron Kay | 139 | 2000-2013 | |
| 18 | Pat Marchitto# | 138 | 2017-2026 | |
| 19 | John Austin# | 135 | 2018-2026 | |
| 20 | Jorge Padilla | 132 | 2009-2021 | |
| 21 | Jon Wagner# | 124 | 2019-2024 | |
| 22 | Mike Beavers | 117 | 2008-2020 | |
| 22 | Juan Gonzalez# | 117 | 2013-2023 | |
| 24 | Yasuro Sugimoto | 112 | 2011-2018 | |
| 25 | Maik Penn# | 109 | 2016-2026 | |
| 26 | Ed Woodside# | 108 | 2022-2026 | |
| 27 | Steve McLaughlin# | 102 | 2022-2026 | |
| 28 | Josh Miller | 94 | 2000-2013 | |
| 29 | Matt Gilfillan | 92 | 2016-2021 | |
| 29 | Julio Gonzalez | 92 | 2007-2019 | |
| 31 | Jason Mata# | 91 | 2016-2022 | |
| 31 | Melvin Vargas | 91 | 2006-2016 | |
| 33 | Fernando Rodriguez | 90 | 2007-2018 | |
| 34 | Jimmy Frew# | 86 | 2018-2026 | |
| 35 | Andrew Baltzley# | 76 | 2020-2025 | |
| 36 | Mitchell Young | 75 | 2000-2007 | |
| 37 | Rich Leggett | 72 | 2000-2005 | |
| 37 | Matt Shaulis | 72 | 2001-2010 | |
| 39 | Jason Armstrong | 71 | 2009-2018 | |
| 40 | Chris Guardiola# | 70 | 2023-2026 | |
| 41 | Dillon Rodriquez# | 69 | 2015-2024 | |
| 42 | Willie Martinez | 68 | 2002-2011 | |
| 42 | Mark Root# | 68 | 2022-2026 | |
| 44 | Sergio Roque | 67 | 2017-2020 | |
| 45 | Tim Hummel# | 65 | 2018-2025 | |
| 45 | Isaiah Mill# | 65 | 2021-2026 | |
| 47 | Blake Benigno# | 63 | 2019-2026 | |
| 47 | Pat Bounds# | 63 | 2025-2026 | |
| 49 | Jaime Flores | 61 | 2014-2019 | |
| 50 | Jose Figueroa | 58 | 2011-2022 | |
| 50 | Heath Graves# | 58 | 2021-2026 | |
| 50 | Adam McCumiskey# | 58 | 2020-2026 | |
| 53 | Ken Shaffer | 56 | 2000-2009 | |
| 53 | Nick Wisniewski# | 56 | 2021-2026 | |
| 55 | Jacob Marley | 54 | 2000-2007 | |
| 55 | Nick Sumney# | 54 | 2022-2026 | |
| 57 | Tsunemi Higaki | 52 | 2007-2016 | |
| 58 | Freddy Bookout | 48 | 2005-2017 | |
| 59 | Raul Arreola# | 47 | 2020-2025 | |
| 59 | Jay Thibodeaux# | 47 | 2014-2024 | |
| 61 | Carlos Lopez | 46 | 2000-2006 | |
| 62 | Jose Gonzales | 45 | 2001-2012 | |
| 62 | Alec Roller | 45 | 2000-2007 | |
| 64 | Bill Garcia | 44 | 2006-2020 | |
| 64 | Willie Torres | 44 | 2010-2016 | |
| 66 | Marco Madrigal# | 43 | 2024-2026 | |
| 67 | Travis Collier | 42 | 2010-2022 | |
| 67 | Josh Kennedy | 42 | 2011-2018 | |
| 69 | Mike States | 41 | 2014-2020 | |
| 70 | Mel Aguilar | 40 | 2015-2021 | |
| 71 | Bronson Clark | 38 | 2007-2018 | |
| 71 | Victor Gonzalez# | 38 | 2010-2026 | |
| 71 | Curtis White | 38 | 2015-2022 | |
| 74 | Joel Harrison | 37 | 2001-2017 | |
| 74 | Casey Schmidt | 37 | 2003-2016 | |
| 74 | Jerry Wilson | 37 | 2000-2006 | |
| 77 | Dan Hartley | 36 | 2001-2010 | |
| 77 | John Jackson | 36 | 2000-2009 | |
| 79 | Mitch Jarka# | 34 | 2020-2025 | |
| 79 | Julio Ramirez | 34 | 2003-2014 | |
| 81 | Emilio Abreu | 32 | 2012-2024 | |
| 81 | Ramiro Martinez | 32 | 2008-2013 | |
| 81 | Joe Robinson# | 32 | 2023-2026 | |
| 84 | Jalen Armour | 31 | 2000-2011 | |
| 84 | Harry Guertin | 31 | 2005-2012 | |
| 84 | Pete Kincaid# | 31 | 2018-2022 | |
| 87 | Bill Geeslin# | 30 | 2016-2026 | |
| 87 | Mike Raia# | 30 | 2024-2026 | |
| 89 | Soroku Asari | 29 | 2009-2015 | |
| 89 | Willie Castanon | 29 | 2011-2020 | |
| 89 | Tristan Conyers | 29 | 2007-2012 | |
| 89 | Mike Monia# | 29 | 2022-2025 | |
| 93 | Jimmy Berry | 28 | 2000-2008 | |
| 93 | Oliver Damon# | 28 | 2016-2026 | |
| 93 | Bobby Revolorio | 28 | 2009-2016 | |
| 93 | Josh Spencer | 28 | 2016-2023 | |
| 93 | Tom Tillotson | 28 | 2007-2016 | |
| 98 | Ricky Guerra | 27 | 2007-2013 | |
| 98 | Pat Mead | 27 | 2015-2018 | |
| 98 | Tony Villarreal# | 27 | 2016-2021 |
