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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Jesus Irizarry | 329 | 2005-2016 | |
| 2 | Jeremy Yamakawa | 293 | 2005-2020 | |
| 3 | Danny Solis | 276 | 2008-2019 | |
| 4 | Jonathan Ashley# | 263 | 2004-2021 | |
| 5 | Emmanuel Haigler | 249 | 2003-2018 | |
| 6 | Pablo Vegas* | 237 | 2000-2012 | |
| 7 | Miles Hayes | 234 | 2000-2012 | |
| 8 | George Reed | 204 | 2000-2011 | |
| 9 | Rich Noble | 203 | 2000-2011 | |
| 10 | Jeff Coleman# | 188 | 2015-2022 | |
| 11 | Gary Dineen | 172 | 2000-2016 | |
| 12 | Brett Byrnes | 171 | 2001-2016 | |
| 12 | Shane Jenkins | 171 | 2000-2013 | |
| 14 | Tony Ochoa# | 167 | 2012-2022 | |
| 15 | Gabriel Perez | 145 | 2006-2018 | |
| 16 | Aaron Kay | 139 | 2000-2013 | |
| 17 | Jorge Padilla | 132 | 2009-2021 | |
| 18 | Pat Marchitto# | 127 | 2017-2022 | |
| 19 | Mike Beavers | 117 | 2008-2020 | |
| 20 | Juan Gonzalez# | 115 | 2013-2022 | |
| 21 | Yasuro Sugimoto | 112 | 2011-2018 | |
| 22 | Josh Miller | 94 | 2000-2013 | |
| 23 | Matt Gilfillan# | 92 | 2016-2021 | |
| 23 | Julio Gonzalez | 92 | 2007-2019 | |
| 25 | Jason Mata# | 91 | 2016-2022 | |
| 25 | Melvin Vargas | 91 | 2006-2016 | |
| 27 | Fernando Rodriguez | 90 | 2007-2018 | |
| 28 | Maik Penn# | 86 | 2016-2022 | |
| 29 | Jon Wagner# | 84 | 2019-2022 | |
| 30 | John Austin# | 75 | 2018-2022 | |
| 30 | Mitchell Young | 75 | 2000-2007 | |
| 32 | Manuel Rosas# | 73 | 2021-2022 | |
| 33 | Rich Leggett | 72 | 2000-2005 | |
| 33 | Matt Shaulis | 72 | 2001-2010 | |
| 35 | Jason Armstrong | 71 | 2009-2018 | |
| 36 | Dillon Rodriquez# | 69 | 2015-2022 | |
| 37 | Willie Martinez | 68 | 2002-2011 | |
| 38 | Sergio Roque | 67 | 2017-2020 | |
| 39 | Jaime Flores | 61 | 2014-2019 | |
| 40 | Jose Figueroa# | 58 | 2011-2022 | |
| 41 | Ken Shaffer | 56 | 2000-2009 | |
| 42 | Tim Hummel# | 54 | 2018-2022 | |
| 42 | Jacob Marley | 54 | 2000-2007 | |
| 44 | Tsunemi Higaki | 52 | 2007-2016 | |
| 45 | Andrew Baltzley# | 49 | 2020-2022 | |
| 46 | Freddy Bookout | 48 | 2005-2017 | |
| 47 | Carlos Lopez | 46 | 2000-2006 | |
| 48 | Jose Gonzales | 45 | 2001-2012 | |
| 48 | Alec Roller | 45 | 2000-2007 | |
| 50 | Bill Garcia | 44 | 2006-2020 | |
| 50 | Willie Torres | 44 | 2010-2016 | |
| 52 | Travis Collier# | 42 | 2010-2022 | |
| 52 | Josh Kennedy | 42 | 2011-2018 | |
| 54 | Mike States | 41 | 2014-2020 | |
| 55 | Mel Aguilar# | 40 | 2015-2021 | |
| 56 | Jimmy Frew# | 39 | 2018-2022 | |
| 57 | Bronson Clark | 38 | 2007-2018 | |
| 57 | Victor Gonzalez# | 38 | 2010-2022 | |
| 57 | Curtis White# | 38 | 2015-2022 | |
| 60 | Joel Harrison | 37 | 2001-2017 | |
| 60 | Casey Schmidt | 37 | 2003-2016 | |
| 60 | Jerry Wilson | 37 | 2000-2006 | |
| 63 | Dan Hartley | 36 | 2001-2010 | |
| 63 | John Jackson | 36 | 2000-2009 | |
| 65 | Julio Ramirez | 34 | 2003-2014 | |
| 66 | Emilio Abreu# | 32 | 2012-2022 | |
| 66 | Ramiro Martinez | 32 | 2008-2013 | |
| 68 | Jalen Armour | 31 | 2000-2011 | |
| 68 | Harry Guertin | 31 | 2005-2012 | |
| 68 | Pete Kincaid# | 31 | 2018-2022 | |
| 71 | Bill Geeslin# | 30 | 2016-2022 | |
| 71 | Jay Thibodeaux# | 30 | 2014-2022 | |
| 73 | Soroku Asari | 29 | 2009-2015 | |
| 73 | Willie Castanon | 29 | 2011-2020 | |
| 73 | Tristan Conyers | 29 | 2007-2012 | |
| 76 | Jimmy Berry | 28 | 2000-2008 | |
| 76 | Bobby Revolorio | 28 | 2009-2016 | |
| 76 | Josh Spencer# | 28 | 2016-2022 | |
| 76 | Tom Tillotson | 28 | 2007-2016 | |
| 80 | Ricky Guerra | 27 | 2007-2013 | |
| 80 | Pat Mead | 27 | 2015-2018 | |
| 80 | Tony Villarreal# | 27 | 2016-2021 | |
| 83 | Mitch Kehr | 26 | 2000-2007 | |
| 84 | Jordan Diaz# | 25 | 2015-2019 | |
| 84 | Nick Drake# | 25 | 2018-2021 | |
| 84 | Dennis Singleton | 25 | 2012-2013 | |
| 84 | Ed Woodside# | 25 | 2022-2022 | |
| 88 | Alex Alvarez | 24 | 2000-2009 | |
| 88 | Osvaldo Avila | 24 | 2012-2021 | |
| 90 | Ryan Clevinger | 23 | 2010-2020 | |
| 90 | Collin Dukes | 23 | 2009-2014 | |
| 90 | Antonio Rodriguez | 23 | 2002-2010 | |
| 93 | Raul Arreola# | 21 | 2020-2022 | |
| 93 | Pete Craft | 21 | 2012-2013 | |
| 93 | Earl Ditto | 21 | 2000-2005 | |
| 96 | Nick Beard | 20 | 2006-2012 | |
| 96 | Mitch Philipp | 20 | 2013-2020 | |
| 96 | Evan Pitts | 20 | 2008-2019 | |
| 96 | Nick Wisniewski# | 20 | 2021-2022 | |
| 100 | Adam Staley | 19 | 2000-2008 |
