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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Jesus Irizarry | 329 | 2005-2016 | |
| 2 | Jeremy Yamakawa | 293 | 2005-2020 | |
| 3 | Danny Solis# | 276 | 2008-2019 | |
| 4 | Jonathan Ashley# | 263 | 2004-2021 | |
| 5 | Emmanuel Haigler | 249 | 2003-2018 | |
| 6 | Pablo Vegas* | 237 | 2000-2012 | |
| 7 | Miles Hayes | 234 | 2000-2012 | |
| 8 | George Reed | 204 | 2000-2011 | |
| 9 | Rich Noble | 203 | 2000-2011 | |
| 10 | Jeff Coleman# | 172 | 2015-2021 | |
| 10 | Gary Dineen | 172 | 2000-2016 | |
| 12 | Brett Byrnes | 171 | 2001-2016 | |
| 12 | Shane Jenkins | 171 | 2000-2013 | |
| 14 | Tony Ochoa# | 151 | 2012-2021 | |
| 15 | Gabriel Perez | 145 | 2006-2018 | |
| 16 | Aaron Kay | 139 | 2000-2013 | |
| 17 | Jorge Padilla# | 132 | 2009-2020 | |
| 18 | Mike Beavers# | 117 | 2008-2020 | |
| 19 | Yasuro Sugimoto# | 112 | 2011-2018 | |
| 20 | Juan Gonzalez# | 109 | 2013-2021 | |
| 21 | Pat Marchitto# | 96 | 2017-2021 | |
| 22 | Josh Miller | 94 | 2000-2013 | |
| 23 | Julio Gonzalez# | 92 | 2007-2019 | |
| 24 | Matt Gilfillan# | 91 | 2016-2021 | |
| 24 | Melvin Vargas | 91 | 2006-2016 | |
| 26 | Fernando Rodriguez | 90 | 2007-2018 | |
| 27 | Mitchell Young | 75 | 2000-2007 | |
| 28 | Rich Leggett | 72 | 2000-2005 | |
| 28 | Matt Shaulis | 72 | 2001-2010 | |
| 30 | Jason Armstrong | 71 | 2009-2018 | |
| 31 | Jason Mata# | 70 | 2016-2021 | |
| 32 | Willie Martinez | 68 | 2002-2011 | |
| 33 | Sergio Roque# | 67 | 2017-2020 | |
| 34 | Jaime Flores# | 61 | 2014-2019 | |
| 35 | Maik Penn# | 59 | 2016-2021 | |
| 36 | Ken Shaffer | 56 | 2000-2009 | |
| 37 | Jose Figueroa# | 54 | 2011-2021 | |
| 37 | Jacob Marley | 54 | 2000-2007 | |
| 39 | Dillon Rodriquez# | 53 | 2015-2021 | |
| 40 | Tsunemi Higaki | 52 | 2007-2016 | |
| 41 | Freddy Bookout | 48 | 2005-2017 | |
| 42 | Carlos Lopez | 46 | 2000-2006 | |
| 43 | Jose Gonzales | 45 | 2001-2012 | |
| 43 | Alec Roller | 45 | 2000-2007 | |
| 45 | Bill Garcia# | 44 | 2006-2020 | |
| 45 | Willie Torres | 44 | 2010-2016 | |
| 47 | John Austin# | 43 | 2018-2021 | |
| 48 | Travis Collier# | 42 | 2010-2021 | |
| 48 | Josh Kennedy# | 42 | 2011-2018 | |
| 50 | Mike States# | 41 | 2014-2020 | |
| 51 | Bronson Clark | 38 | 2007-2018 | |
| 51 | Victor Gonzalez# | 38 | 2010-2021 | |
| 51 | Tim Hummel# | 38 | 2018-2021 | |
| 54 | Mel Aguilar# | 37 | 2015-2020 | |
| 54 | Joel Harrison | 37 | 2001-2017 | |
| 54 | Casey Schmidt | 37 | 2003-2016 | |
| 54 | Jerry Wilson | 37 | 2000-2006 | |
| 58 | Dan Hartley | 36 | 2001-2010 | |
| 58 | John Jackson | 36 | 2000-2009 | |
| 60 | Julio Ramirez | 34 | 2003-2014 | |
| 60 | Jon Wagner# | 34 | 2019-2021 | |
| 62 | Emilio Abreu# | 32 | 2012-2021 | |
| 62 | Ramiro Martinez | 32 | 2008-2013 | |
| 64 | Jalen Armour | 31 | 2000-2011 | |
| 64 | Harry Guertin | 31 | 2005-2012 | |
| 64 | Pete Kincaid# | 31 | 2018-2021 | |
| 67 | Soroku Asari | 29 | 2009-2015 | |
| 67 | Willie Castanon# | 29 | 2011-2020 | |
| 67 | Tristan Conyers | 29 | 2007-2012 | |
| 70 | Jimmy Berry | 28 | 2000-2008 | |
| 70 | Bobby Revolorio | 28 | 2009-2016 | |
| 70 | Tom Tillotson | 28 | 2007-2016 | |
| 73 | Ricky Guerra | 27 | 2007-2013 | |
| 73 | Pat Mead | 27 | 2015-2018 | |
| 73 | Tony Villarreal# | 27 | 2016-2020 | |
| 76 | Mitch Kehr | 26 | 2000-2007 | |
| 77 | Jordan Diaz# | 25 | 2015-2019 | |
| 77 | Nick Drake# | 25 | 2018-2021 | |
| 77 | Dennis Singleton | 25 | 2012-2013 | |
| 80 | Alex Alvarez | 24 | 2000-2009 | |
| 80 | Osvaldo Avila# | 24 | 2012-2020 | |
| 82 | Ryan Clevinger# | 23 | 2010-2020 | |
| 82 | Collin Dukes | 23 | 2009-2014 | |
| 82 | Antonio Rodriguez | 23 | 2002-2010 | |
| 85 | Andrew Baltzley# | 22 | 2020-2021 | |
| 86 | Pete Craft | 21 | 2012-2013 | |
| 86 | Earl Ditto | 21 | 2000-2005 | |
| 86 | Jimmy Frew# | 21 | 2018-2021 | |
| 89 | Nick Beard | 20 | 2006-2012 | |
| 89 | Mitch Philipp# | 20 | 2013-2020 | |
| 89 | Evan Pitts | 20 | 2008-2019 | |
| 92 | Adam Staley | 19 | 2000-2008 | |
| 93 | Ron Forrest | 18 | 2004-2007 | |
| 93 | Luis Martinez | 18 | 2012-2015 | |
| 93 | Curtis White# | 18 | 2015-2020 | |
| 96 | Bob Ortiz | 17 | 2011-2018 | |
| 96 | Jay Thibodeaux# | 17 | 2014-2021 | |
| 98 | Oliver Damon# | 16 | 2016-2021 | |
| 98 | Dusty Pedersen | 16 | 2012-2018 | |
| 100 | Yu-xing Cheng | 15 | 2008-2017 |
