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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Brian LaFever | 351 | 2003-2018 | |
| 2 | Pat Howe | 316 | 2005-2019 | |
| 3 | David Perdomo | 291 | 2000-2012 | |
| 4 | Adam Nance | 286 | 2008-2020 | |
| 5 | Jason Brown | 279 | 2007-2021 | |
| 6 | Luis Soto | 275 | 2005-2017 | |
| 7 | Rogelio Sanchez | 239 | 2001-2016 | |
| 8 | Dan Walker | 225 | 2001-2015 | |
| 9 | C.J. Sidney | 219 | 2000-2010 | |
| 10 | Andrew DeGroff | 217 | 2000-2010 | |
| 11 | Willie Granados | 215 | 2000-2010 | |
| 12 | Clark Owens# | 201 | 2018-2025 | |
| 13 | Chris Beasley# | 198 | 2016-2025 | |
| 14 | Andre Cunningham | 194 | 2008-2019 | |
| 15 | Kevin Iskra | 192 | 2010-2019 | |
| 16 | Rodolfo Alvarez | 187 | 2000-2008 | |
| 17 | J.R. Pohlman | 184 | 2000-2008 | |
| 18 | Joel Harrison | 169 | 2001-2017 | |
| 18 | Danny Pierce# | 169 | 2021-2026 | |
| 20 | Johnny Ortega* | 162 | 2000-2016 | |
| 20 | Jeremy Yamakawa* | 162 | 2005-2020 | |
| 22 | Danny Cruz | 156 | 2000-2011 | |
| 23 | Aharon Kroyan# | 150 | 2019-2025 | |
| 24 | Derek Maher# | 148 | 2019-2026 | |
| 25 | Jon Pitts# | 143 | 2014-2026 | |
| 26 | Mitch Philipp | 142 | 2013-2020 | |
| 27 | Brian Shultz# | 122 | 2018-2026 | |
| 28 | Eric Hayes# | 121 | 2022-2026 | |
| 29 | Jim Mireles | 120 | 2007-2015 | |
| 30 | Bobby Mendoza# | 119 | 2018-2026 | |
| 31 | Jim Anderson# | 117 | 2021-2026 | |
| 32 | Ben Callahan# | 114 | 2020-2025 | |
| 33 | Joham Fafes | 111 | 2004-2014 | |
| 34 | Dan Brewer# | 106 | 2018-2024 | |
| 35 | Matt Blevins# | 105 | 2023-2026 | |
| 35 | Julio Ramirez | 105 | 2003-2014 | |
| 35 | Mike Thompson | 105 | 2014-2023 | |
| 38 | Tim Schellin# | 102 | 2021-2025 | |
| 39 | Steve Wooldridge | 98 | 2018-2022 | |
| 40 | Josh Miller | 95 | 2000-2013 | |
| 41 | Jon Atwell | 92 | 2009-2019 | |
| 41 | Mitchell Young | 92 | 2000-2007 | |
| 43 | Sean Drummond | 90 | 2000-2007 | |
| 43 | Ernesto Ramirez# | 90 | 2017-2026 | |
| 45 | Keith Brosch# | 89 | 2021-2026 | |
| 46 | Eric Bradstreet | 88 | 2016-2022 | |
| 46 | Luis Pompa | 88 | 2012-2019 | |
| 48 | Danny Solis | 86 | 2008-2019 | |
| 48 | D.J. Van Diest# | 86 | 2022-2026 | |
| 50 | Tsunemi Higaki | 84 | 2007-2016 | |
| 51 | Caleb Strouse | 83 | 2000-2014 | |
| 52 | George Dashiell | 82 | 2000-2009 | |
| 53 | Jeremy Moore# | 81 | 2014-2024 | |
| 54 | Russ Bansemer | 80 | 2010-2019 | |
| 55 | Matt Lawson | 77 | 2017-2022 | |
| 56 | Matt O'Brien | 75 | 2000-2006 | |
| 57 | Juan Lopez | 71 | 2012-2018 | |
| 58 | Josh Terrien | 68 | 2017-2022 | |
| 59 | Ian McKibbins# | 67 | 2019-2022 | |
| 59 | John Piscitelli# | 67 | 2022-2026 | |
| 61 | David Dutton | 66 | 2004-2015 | |
| 62 | Jay Thibodeaux# | 65 | 2014-2024 | |
| 63 | Miles Hayes | 64 | 2000-2012 | |
| 64 | Jonathan Ashley | 63 | 2004-2021 | |
| 64 | Tony Ochoa | 63 | 2012-2024 | |
| 66 | Willie Kirkham# | 62 | 2022-2026 | |
| 67 | Nelson Ziersch# | 60 | 2022-2026 | |
| 68 | David Atchley | 58 | 2008-2016 | |
| 68 | Chao-yang Shui | 58 | 2002-2008 | |
| 70 | Alfonso Alvarez | 57 | 2013-2019 | |
| 70 | Vince Austin | 57 | 2015-2019 | |
| 70 | Chris Cocks | 57 | 2005-2011 | |
| 73 | Mike Green# | 55 | 2020-2026 | |
| 73 | Justin LaMontagne | 55 | 2014-2016 | |
| 73 | Gabriel Perez | 55 | 2006-2018 | |
| 73 | Tom Tillotson | 55 | 2007-2016 | |
| 73 | Billy Totten# | 55 | 2021-2026 | |
| 78 | Tadao Kitagawa | 54 | 2001-2010 | |
| 78 | David Maynard | 54 | 2006-2013 | |
| 80 | Joe Engle | 53 | 2012-2018 | |
| 81 | Jose Duarte | 50 | 2018-2021 | |
| 82 | Gustavo Orozco# | 49 | 2021-2025 | |
| 83 | John Jones | 48 | 2000-2003 | |
| 84 | Dustin Houston | 47 | 2006-2016 | |
| 84 | Corey Pope# | 47 | 2023-2026 | |
| 84 | Josh Spencer | 47 | 2016-2023 | |
| 87 | Emilio Abreu | 46 | 2012-2024 | |
| 87 | Jonathan Rivera | 46 | 2010-2018 | |
| 89 | A.J. Cook# | 45 | 2020-2024 | |
| 90 | Mike Melin | 44 | 2015-2020 | |
| 91 | Skyler Fundis# | 43 | 2024-2026 | |
| 92 | Jason Armstrong | 42 | 2009-2018 | |
| 92 | German Galvan | 42 | 2014-2017 | |
| 92 | Jerry Robinson# | 42 | 2023-2026 | |
| 95 | Matt Liebler | 41 | 2015-2020 | |
| 95 | Mark Torres# | 41 | 2023-2026 | |
| 97 | Ramon Hernandez | 40 | 2002-2014 | |
| 97 | Gus Marquez# | 40 | 2019-2023 | |
| 99 | Steve Ausman | 39 | 2008-2019 | |
| 99 | Dale Day# | 39 | 2023-2026 |
