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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Michael Mendez | 486 | 2007-2020 | |
| 2 | John Karpf | 485 | 2004-2021 | |
| 3 | Jason Wilson* | 470 | 2000-2016 | |
| 4 | Chris Bryan | 418 | 2007-2023 | |
| 5 | Mitsuaki Sakaguchi | 219 | 2008-2016 | |
| 6 | David Phelps | 173 | 2006-2020 | |
| 7 | Brett Byrnes | 163 | 2001-2016 | |
| 8 | Edwin Gomez | 160 | 2000-2008 | |
| 8 | Steve Reid | 160 | 2000-2008 | |
| 10 | Bill Larrain | 153 | 2009-2023 | |
| 11 | Bill Geeslin# | 147 | 2016-2024 | |
| 12 | Dave Van Natta | 140 | 2000-2009 | |
| 13 | Austin Compton# | 130 | 2015-2024 | |
| 14 | Jerry Jamieson | 127 | 2000-2005 | |
| 15 | David Janson | 117 | 2006-2015 | |
| 16 | Marcos Amador | 86 | 2010-2019 | |
| 17 | Bob Cook# | 82 | 2016-2024 | |
| 17 | Alec Pavelka# | 82 | 2013-2023 | |
| 17 | Javier Saiz | 82 | 2000-2008 | |
| 20 | Joe Fossett | 81 | 2005-2016 | |
| 21 | Tommy Martin | 80 | 2011-2019 | |
| 21 | Nick Pratt# | 80 | 2014-2024 | |
| 23 | John Harris# | 78 | 2013-2022 | |
| 24 | Tony Diaz | 75 | 2000-2005 | |
| 25 | Joaquin Bermudez | 74 | 2009-2018 | |
| 26 | Henry Cortez# | 67 | 2021-2024 | |
| 27 | Adam Ponder | 62 | 2000-2011 | |
| 28 | Chris Ceccoli | 60 | 2000-2007 | |
| 29 | Matt Munsey | 58 | 2002-2011 | |
| 30 | Ângelo Sedas | 57 | 2012-2020 | |
| 31 | Pat Grayson# | 55 | 2019-2023 | |
| 32 | Brian O'Bryan | 53 | 2000-2007 | |
| 32 | Ethan Robertson | 53 | 2000-2009 | |
| 34 | Danny Lebron# | 52 | 2019-2024 | |
| 34 | Chance Smith# | 52 | 2020-2024 | |
| 34 | Chad Turner | 52 | 2011-2019 | |
| 37 | Inácio Borralha | 51 | 2014-2019 | |
| 38 | Zack Husley# | 49 | 2022-2024 | |
| 39 | Carlos Martinez | 48 | 2003-2016 | |
| 39 | Robby Penland# | 48 | 2016-2024 | |
| 41 | Paul McCarthy# | 47 | 2018-2024 | |
| 41 | Dusty Ward# | 47 | 2023-2024 | |
| 43 | Jeff Beeson# | 46 | 2018-2024 | |
| 43 | Jeff Kerner | 46 | 2005-2019 | |
| 45 | David Duthie# | 45 | 2021-2024 | |
| 46 | Dustin Lanum | 44 | 2009-2015 | |
| 46 | Hasan Raif | 44 | 2000-2008 | |
| 48 | Jason Ramsey# | 43 | 2015-2024 | |
| 48 | Severo Salcido# | 43 | 2013-2023 | |
| 50 | Jon Dearman# | 39 | 2020-2024 | |
| 50 | Brian Myers# | 39 | 2021-2024 | |
| 52 | Jared Priest# | 37 | 2016-2024 | |
| 53 | Ben Barbone# | 36 | 2020-2024 | |
| 54 | Myeong-hwan Pak | 35 | 2010-2016 | |
| 55 | Tyshawn Cole | 34 | 2006-2013 | |
| 55 | Mike Lynn# | 34 | 2017-2022 | |
| 57 | Al Crawford | 33 | 2005-2013 | |
| 57 | Oscar Fraga | 33 | 2005-2011 | |
| 57 | Jesse Pratt# | 33 | 2016-2021 | |
| 57 | Willie Rios | 33 | 2015-2016 | |
| 57 | Victor Santa Cruz | 33 | 2016-2022 | |
| 57 | Bill Shahan# | 33 | 2018-2024 | |
| 63 | Jason Cox# | 32 | 2019-2024 | |
| 63 | Marcos Santiago# | 32 | 2021-2024 | |
| 65 | Sam Leone | 31 | 2007-2013 | |
| 65 | Melvin Lizalde | 31 | 2000-2005 | |
| 67 | Ruben Alamo# | 30 | 2020-2024 | |
| 67 | Cory Sperber# | 30 | 2016-2023 | |
| 69 | Rick Joyce# | 29 | 2021-2023 | |
| 69 | Rob Wise | 29 | 2007-2013 | |
| 69 | Armando Zuniga | 29 | 2015-2021 | |
| 72 | Andrew Evans | 28 | 2010-2021 | |
| 72 | Nate Volk# | 28 | 2017-2024 | |
| 74 | Isaiah Moffett | 27 | 2006-2017 | |
| 74 | Casey Rymer | 27 | 2000-2002 | |
| 76 | Justin Barrett | 26 | 2000-2007 | |
| 76 | Jayden Gamble | 26 | 2000-2006 | |
| 76 | Robby Mills | 26 | 2013-2020 | |
| 79 | Tiberio Donelli | 25 | 2001-2011 | |
| 79 | Mike Haak | 25 | 2006-2016 | |
| 79 | Ryan Kasper | 25 | 2000-2004 | |
| 79 | Andrew Lau | 25 | 2013-2018 | |
| 79 | Ivan Rodriguez | 25 | 2000-2009 | |
| 79 | Ryan Young | 25 | 2011-2017 | |
| 85 | Rich Gomez | 24 | 2000-2008 | |
| 85 | Dave Jones | 24 | 2017-2022 | |
| 85 | Danny Sanchez | 24 | 2000-2011 | |
| 88 | J.P. Baldwin# | 23 | 2018-2023 | |
| 88 | Tim Morales | 23 | 2011-2017 | |
| 88 | Danny Ramirez | 23 | 2007-2014 | |
| 88 | Victor Ramos | 23 | 2018-2019 | |
| 88 | Jeremiah Simpson | 23 | 2000-2004 | |
| 93 | Nick Brandt | 22 | 2013-2016 | |
| 93 | Jose Fontes | 22 | 2014-2021 | |
| 95 | Willie Arellanes | 21 | 2000-2009 | |
| 95 | Manny Benitez | 21 | 2000-2013 | |
| 95 | Jeremy Day | 21 | 2009-2015 | |
| 95 | Gary Draeger# | 21 | 2016-2024 | |
| 95 | Keith Orner | 21 | 2000-2009 | |
| 95 | Jasper Sloan | 21 | 2002-2011 |
