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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Jonathan Ashley# | 637 | 2004-2021 | |
| 2 | Yasuzo Yamaoka | 553 | 2005-2019 | |
| 3 | Michael Mendez# | 486 | 2007-2020 | |
| 4 | Joel Harrison | 479 | 2001-2017 | |
| 4 | John Karpf# | 479 | 2004-2021 | |
| 6 | Jonathan Ellis# | 470 | 2009-2021 | |
| 6 | Jason Wilson | 470 | 2000-2016 | |
| 8 | Jeremy Yamakawa | 455 | 2005-2020 | |
| 9 | Chris Wolf | 450 | 2000-2016 | |
| 10 | Matt Vickers | 444 | 2000-2015 | |
| 11 | Chris Bryan# | 417 | 2007-2021 | |
| 12 | Pablo Vegas* | 414 | 2000-2012 | |
| 13 | Brian Klomp# | 406 | 2003-2019 | |
| 14 | Brian LaFever | 404 | 2003-2018 | |
| 15 | Dan Walker | 386 | 2001-2015 | |
| 16 | Omar Pena | 381 | 2000-2011 | |
| 17 | Mike Barriga | 378 | 2000-2010 | |
| 18 | Brett Byrnes | 367 | 2001-2016 | |
| 19 | Danny Solis# | 362 | 2008-2019 | |
| 20 | Victor Gonzalez# | 358 | 2010-2021 | |
| 21 | Dan Rodriguez | 345 | 2001-2013 | |
| 22 | Logan Greening | 338 | 2001-2014 | |
| 23 | Jason Brown# | 336 | 2007-2020 | |
| 24 | Pat Howe | 335 | 2005-2019 | |
| 25 | Jesus Irizarry | 329 | 2005-2016 | |
| 26 | Carlos Escalera* | 323 | 2000-2008 | |
| 27 | Eric Druin# | 321 | 2011-2021 | |
| 28 | Adam Nance# | 317 | 2008-2020 | |
| 29 | Richard Green | 311 | 2000-2012 | |
| 30 | Rogelio Sanchez | 306 | 2001-2016 | |
| 31 | Zach Swint | 304 | 2001-2016 | |
| 32 | Miles Hayes | 298 | 2000-2012 | |
| 33 | Jon Rouse | 295 | 2004-2018 | |
| 34 | Paul Pittman# | 292 | 2013-2021 | |
| 35 | Pat Dickson | 291 | 2007-2017 | |
| 35 | David Perdomo | 291 | 2000-2012 | |
| 35 | Luis Soto | 291 | 2005-2017 | |
| 38 | Ramon Hernandez | 282 | 2002-2014 | |
| 39 | Barry Evans | 276 | 2000-2007 | |
| 39 | Leo Serna# | 276 | 2014-2021 | |
| 41 | Danny Horner | 271 | 2004-2015 | |
| 42 | Danny Cruz | 266 | 2000-2011 | |
| 43 | Rich Noble | 262 | 2000-2011 | |
| 44 | Emmanuel Haigler | 261 | 2003-2018 | |
| 44 | Israel Salazar | 261 | 2004-2016 | |
| 46 | David Phelps# | 259 | 2006-2020 | |
| 47 | Kevin Galovich | 258 | 2004-2015 | |
| 48 | Daniel Jackson | 254 | 2000-2011 | |
| 49 | Armando Cisneros | 253 | 2000-2012 | |
| 50 | Matt Karlowski# | 249 | 2012-2020 | |
| 51 | Billy Porter# | 248 | 2011-2021 | |
| 51 | Ricky Villarreal | 248 | 2000-2009 | |
| 53 | Caleb Strouse | 246 | 2000-2014 | |
| 54 | Austin Compton# | 241 | 2015-2021 | |
| 55 | Juan Garcia# | 238 | 2010-2021 | |
| 56 | Carlos Martinez | 237 | 2003-2016 | |
| 57 | Dustin Williams | 235 | 2005-2015 | |
| 58 | Mitsuaki Sakaguchi | 232 | 2008-2016 | |
| 58 | Jose Velasquez | 232 | 2000-2010 | |
| 60 | Rodolfo Alvarez | 230 | 2000-2008 | |
| 61 | Ken Bennett | 223 | 2000-2009 | |
| 62 | Jonathan Cabrera# | 222 | 2008-2021 | |
| 63 | Andrew DeGroff | 221 | 2000-2010 | |
| 64 | C.J. Sidney | 219 | 2000-2010 | |
| 65 | Josh Miller | 216 | 2000-2013 | |
| 66 | Willie Granados | 215 | 2000-2010 | |
| 67 | Casey Schmidt | 214 | 2003-2016 | |
| 68 | Jon Pitts# | 208 | 2014-2021 | |
| 69 | Luis Vasquez | 207 | 2006-2016 | |
| 70 | Devon Randolph | 206 | 2000-2007 | |
| 71 | Andre Cunningham | 205 | 2008-2019 | |
| 72 | George Reed | 204 | 2000-2011 | |
| 73 | Mike Plocher | 203 | 2000-2009 | |
| 74 | Jon Hager# | 202 | 2010-2021 | |
| 75 | Gabriel Perez | 200 | 2006-2018 | |
| 75 | Alec Roller | 200 | 2000-2007 | |
| 77 | Pablo Barajas# | 198 | 2011-2021 | |
| 77 | Joham Fafes | 198 | 2004-2014 | |
| 77 | Leo Orozco# | 198 | 2016-2021 | |
| 77 | Julio Ramirez | 198 | 2003-2014 | |
| 81 | Travis Collier# | 194 | 2010-2021 | |
| 82 | Kevin Iskra | 192 | 2010-2019 | |
| 82 | Alberto Ojeda | 192 | 2002-2016 | |
| 84 | Victor Garcia# | 185 | 2010-2020 | |
| 85 | Kazumasa Mochizuki | 184 | 2002-2011 | |
| 85 | J.R. Pohlman | 184 | 2000-2008 | |
| 87 | Bob Johnson | 182 | 2000-2012 | |
| 88 | Shane Jenkins | 181 | 2000-2013 | |
| 89 | Jim Jacobs# | 179 | 2015-2021 | |
| 90 | Tony Ochoa# | 178 | 2012-2021 | |
| 91 | Ryan Griffitt# | 174 | 2013-2021 | |
| 92 | Juan Andrade# | 172 | 2017-2021 | |
| 92 | Jeff Coleman# | 172 | 2015-2021 | |
| 92 | Gary Dineen | 172 | 2000-2016 | |
| 95 | Mike Sheldon | 171 | 2002-2017 | |
| 95 | Bobby Tapia# | 171 | 2008-2021 | |
| 97 | Emilio Abreu# | 170 | 2012-2021 | |
| 97 | Joe Handler# | 170 | 2015-2021 | |
| 97 | Gong-sun Thum# | 170 | 2011-2020 | |
| 100 | Jon Atwell | 168 | 2009-2019 |
