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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Jonathan Ashley# | 664 | 2004-2021 | |
| 2 | Yasuzo Yamaoka | 553 | 2005-2019 | |
| 3 | Jonathan Ellis# | 499 | 2009-2021 | |
| 4 | Michael Mendez# | 486 | 2007-2020 | |
| 5 | John Karpf# | 485 | 2004-2021 | |
| 6 | Joel Harrison | 479 | 2001-2017 | |
| 7 | Jason Wilson* | 470 | 2000-2016 | |
| 8 | Jeremy Yamakawa | 455 | 2005-2020 | |
| 9 | Chris Wolf | 450 | 2000-2016 | |
| 10 | Matt Vickers | 444 | 2000-2015 | |
| 11 | Chris Bryan# | 427 | 2007-2021 | |
| 12 | Pablo Vegas* | 414 | 2000-2012 | |
| 13 | Brian Klomp | 406 | 2003-2019 | |
| 14 | Brian LaFever | 404 | 2003-2018 | |
| 15 | Dan Walker | 386 | 2001-2015 | |
| 16 | Omar Pena | 381 | 2000-2011 | |
| 17 | Mike Barriga | 378 | 2000-2010 | |
| 18 | Victor Gonzalez# | 372 | 2010-2021 | |
| 19 | Brett Byrnes | 367 | 2001-2016 | |
| 20 | Danny Solis | 362 | 2008-2019 | |
| 21 | Dan Rodriguez | 345 | 2001-2013 | |
| 22 | Logan Greening | 338 | 2001-2014 | |
| 23 | Jason Brown | 337 | 2007-2021 | |
| 24 | Pat Howe | 335 | 2005-2019 | |
| 25 | Eric Druin# | 333 | 2011-2021 | |
| 26 | Jesus Irizarry | 329 | 2005-2016 | |
| 27 | Carlos Escalera* | 323 | 2000-2008 | |
| 28 | Adam Nance# | 317 | 2008-2020 | |
| 29 | Richard Green | 311 | 2000-2012 | |
| 30 | Paul Pittman# | 308 | 2013-2021 | |
| 31 | Rogelio Sanchez | 306 | 2001-2016 | |
| 32 | Zach Swint | 304 | 2001-2016 | |
| 33 | Leo Serna# | 301 | 2014-2021 | |
| 34 | Miles Hayes | 298 | 2000-2012 | |
| 35 | Jon Rouse | 295 | 2004-2018 | |
| 36 | Pat Dickson | 291 | 2007-2017 | |
| 36 | David Perdomo | 291 | 2000-2012 | |
| 36 | Luis Soto | 291 | 2005-2017 | |
| 39 | Ramon Hernandez | 282 | 2002-2014 | |
| 40 | Barry Evans | 276 | 2000-2007 | |
| 41 | Danny Horner | 271 | 2004-2015 | |
| 42 | Austin Compton# | 266 | 2015-2021 | |
| 42 | Danny Cruz | 266 | 2000-2011 | |
| 44 | Rich Noble | 262 | 2000-2011 | |
| 44 | Billy Porter# | 262 | 2011-2021 | |
| 46 | Emmanuel Haigler | 261 | 2003-2018 | |
| 46 | Israel Salazar | 261 | 2004-2016 | |
| 48 | David Phelps | 259 | 2006-2020 | |
| 49 | Kevin Galovich | 258 | 2004-2015 | |
| 50 | Daniel Jackson | 254 | 2000-2011 | |
| 51 | Armando Cisneros | 253 | 2000-2012 | |
| 52 | Matt Karlowski# | 249 | 2012-2021 | |
| 53 | Ricky Villarreal | 248 | 2000-2009 | |
| 54 | Caleb Strouse | 246 | 2000-2014 | |
| 55 | Juan Garcia# | 242 | 2010-2021 | |
| 56 | Carlos Martinez | 237 | 2003-2016 | |
| 57 | Dustin Williams | 235 | 2005-2015 | |
| 58 | Jonathan Cabrera# | 233 | 2008-2021 | |
| 59 | Mitsuaki Sakaguchi | 232 | 2008-2016 | |
| 59 | Jose Velasquez | 232 | 2000-2010 | |
| 61 | Rodolfo Alvarez | 230 | 2000-2008 | |
| 62 | Jon Pitts# | 229 | 2014-2021 | |
| 63 | Ken Bennett | 223 | 2000-2009 | |
| 63 | Leo Orozco# | 223 | 2016-2021 | |
| 65 | Andrew DeGroff | 221 | 2000-2010 | |
| 66 | C.J. Sidney | 219 | 2000-2010 | |
| 67 | Josh Miller | 216 | 2000-2013 | |
| 68 | Pablo Barajas# | 215 | 2011-2021 | |
| 68 | Willie Granados | 215 | 2000-2010 | |
| 70 | Casey Schmidt | 214 | 2003-2016 | |
| 71 | Jon Hager# | 207 | 2010-2021 | |
| 71 | Luis Vasquez | 207 | 2006-2016 | |
| 73 | Devon Randolph | 206 | 2000-2007 | |
| 74 | Andre Cunningham | 205 | 2008-2019 | |
| 75 | George Reed | 204 | 2000-2011 | |
| 76 | Mike Plocher | 203 | 2000-2009 | |
| 77 | Gabriel Perez | 200 | 2006-2018 | |
| 77 | Alec Roller | 200 | 2000-2007 | |
| 79 | Travis Collier# | 199 | 2010-2021 | |
| 80 | Joham Fafes | 198 | 2004-2014 | |
| 80 | Julio Ramirez | 198 | 2003-2014 | |
| 82 | Juan Andrade# | 197 | 2017-2021 | |
| 83 | Tony Ochoa# | 193 | 2012-2021 | |
| 84 | Kevin Iskra | 192 | 2010-2019 | |
| 84 | Jim Jacobs# | 192 | 2015-2021 | |
| 84 | Alberto Ojeda* | 192 | 2002-2016 | |
| 87 | Joe Handler# | 188 | 2015-2021 | |
| 88 | Jeff Coleman# | 185 | 2015-2021 | |
| 88 | Victor Garcia# | 185 | 2010-2020 | |
| 90 | Chris Beasley# | 184 | 2016-2021 | |
| 90 | Kazumasa Mochizuki | 184 | 2002-2011 | |
| 90 | J.R. Pohlman | 184 | 2000-2008 | |
| 93 | Bob Johnson | 182 | 2000-2012 | |
| 94 | Shane Jenkins | 181 | 2000-2013 | |
| 95 | Ryan Griffitt# | 180 | 2013-2021 | |
| 96 | Tyler Jordan# | 178 | 2011-2021 | |
| 96 | Bobby Tapia# | 178 | 2008-2021 | |
| 98 | Emilio Abreu# | 177 | 2012-2021 | |
| 99 | Gary Dineen | 172 | 2000-2016 | |
| 99 | Ernesto Ramirez# | 172 | 2017-2021 |
