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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Tomas Adon | 1.289 | 2004 | |
| 2 | Xavier Cooper# | 1.513 | 2014 | |
| 3 | Hector Estrella# | 1.534 | 2019 | |
| 4 | Ryan Henry# | 1.550 | 2020 | |
| 5 | Jonathan Roten# | 1.585 | 2014 | |
| 6 | Mario Pellot | 1.709 | 2003 | |
| 7 | Mario Santos# | 1.734 | 2018 | |
| 8 | Tom Henwood# | 1.773 | 2014 | |
| 9 | Adrian Radecki# | 1.782 | 2011 | |
| 10 | Zachary Christman# | 1.783 | 2013 | |
| 11 | Mario Castillon | 1.789 | 2005 | |
| 12 | Frank Rodriguez | 1.793 | 2012 | |
| 13 | Evan Pullman# | 1.808 | 2019 | |
| 14 | Matt Graham# | 1.892 | 2019 | |
| 15 | Nate Stout# | 1.901 | 2018 | |
| 16 | C.J. Mejia | 1.936 | 2017 | |
| 17 | Josh Hoffman | 1.937 | 2014 | |
| 18 | Adam Webb | 1.942 | 2004 | |
| 19 | Ivan Salgado | 1.960 | 2017 | |
| 20 | Mike Davis# | 1.974 | 2020 | |
| 21 | Danny Michel | 1.977 | 2002 | |
| 22 | Jeff Mitchell# | 1.998 | 2018 | |
| 23 | Seth Carey | 2.021 | 2003 | |
| 24 | Joo-seok Kim | 2.034 | 2011 | |
| 24 | Dante Ramos# | 2.034 | 2016 | |
| 26 | Adam Haire | 2.035 | 2018 | |
| 27 | Ray Dappen# | 2.043 | 2020 | |
| 28 | T.J. Harrison# | 2.047 | 2016 | |
| 29 | Billy Westcott# | 2.066 | 2017 | |
| 30 | Ronnie Roberson# | 2.073 | 2015 | |
| 31 | Justin Smith | 2.081 | 2014 | |
| 32 | Gil Johnson | 2.109 | 2003 | |
| 33 | Danny Adame | 2.115 | 2002 | |
| 34 | Ronnie Roberson# | 2.143 | 2014 | |
| 35 | Owen Kase# | 2.146 | 2012 | |
| 36 | Omar Navarrete# | 2.186 | 2016 | |
| 37 | Glenn Ward# | 2.192 | 2020 | |
| 38 | Marcos Sanchez | 2.196 | 2000 | |
| 39 | Albert Fabian# | 2.198 | 2013 | |
| 40 | John Woodburn | 2.200 | 2014 | |
| 41 | Ben Murphy# | 2.218 | 2015 | |
| 42 | Dillon Moyer | 2.226 | 2001 | |
| 43 | Mike Johnson | 2.227 | 2007 | |
| 44 | Danny Turnipseed | 2.229 | 2016 | |
| 45 | Arturo Jimenez | 2.233 | 2003 | |
| 46 | Cortez Trevino# | 2.237 | 2017 | |
| 47 | Alfredo Garza# | 2.250 | 2012 | |
| 48 | Eduardo Ramos# | 2.260 | 2020 | |
| 49 | Juan Fernandez# | 2.278 | 2018 | |
| 50 | Danny Gonzalez | 2.282 | 2013 | |
| 51 | Ben Fox | 2.287 | 2013 | |
| 52 | Kyle Chamberlin# | 2.302 | 2018 | |
| 53 | Moises Gonzalez# | 2.309 | 2020 | |
| 54 | Cesar Chairez# | 2.314 | 2019 | |
| 55 | Adrian Lough# | 2.328 | 2015 | |
| 56 | Joe Stanley# | 2.339 | 2018 | |
| 57 | John Holifield | 2.343 | 2012 | |
| 58 | Daniel Harris | 2.350 | 2012 | |
| 59 | Juan Fernandez# | 2.360 | 2020 | |
| 60 | Brian Tucker | 2.373 | 2000 | |
| 61 | Jeremy Maglio | 2.389 | 2006 | |
| 62 | Josh Hoffman | 2.402 | 2012 | |
| 63 | Antonio Sanchez# | 2.421 | 2017 | |
| 64 | Gustavo Hernandez | 2.428 | 2013 | |
| 65 | Rafael Alcaraz | 2.439 | 2011 | |
| 66 | Gabriel Jordan | 2.450 | 2005 | |
| 67 | Brian Prince# | 2.455 | 2011 | |
| 68 | John Pyles# | 2.459 | 2019 | |
| 69 | Cortez Trevino# | 2.470 | 2018 | |
| 70 | Willie Lopez | 2.483 | 2010 | |
| 71 | Juan Vasquez# | 2.486 | 2018 | |
| 72 | Mike Davis# | 2.490 | 2015 | |
| 72 | Erik Guinn | 2.490 | 2014 | |
| 74 | Kyle Chamberlin# | 2.491 | 2020 | |
| 75 | Raquel Cochat | 2.498 | 2014 | |
| 76 | Mike Roper | 2.502 | 2011 | |
| 77 | Carlos Garcia | 2.513 | 2011 | |
| 78 | Willie Bahena# | 2.514 | 2020 | |
| 79 | Dustin Weldin | 2.518 | 2017 | |
| 79 | Jake Plott# | 2.518 | 2016 | |
| 81 | Antonio Sanchez | 2.522 | 2013 | |
| 82 | Ryan Iverson | 2.523 | 2004 | |
| 83 | Victor Medina | 2.524 | 2007 | |
| 84 | Mel Duran# | 2.534 | 2019 | |
| 85 | Kyle Chamberlin# | 2.542 | 2019 | |
| 86 | Beau Larson# | 2.564 | 2019 | |
| 87 | Juan Diaz | 2.566 | 2008 | |
| 88 | Rick Lee# | 2.574 | 2018 | |
| 88 | Chris Shifflett | 2.574 | 2002 | |
| 90 | Leo Medina | 2.578 | 2001 | |
| 91 | Cesar Nunez | 2.583 | 2009 | |
| 92 | Juan Vasquez# | 2.593 | 2017 | |
| 93 | Angel Aragon | 2.605 | 2015 | |
| 94 | Albert Espinoza# | 2.607 | 2017 | |
| 94 | Derrick Espinosa# | 2.607 | 2020 | |
| 96 | R.J. Lawhead# | 2.608 | 2018 | |
| 97 | Mario Pellot | 2.627 | 2002 | |
| 98 | Byron Stanton# | 2.637 | 2018 | |
| 99 | Mike Quinn | 2.643 | 2012 | |
| 100 | Mario Munoz | 2.652 | 2000 |
