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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Cameron Anderson | 177 | 2012-2016 | |
| 2 | Chris Manning | 157 | 2011-2016 | |
| 3 | Joel Atkinson | 146 | 2012-2021 | |
| 4 | Jesus Garcia# | 145 | 2018-2025 | |
| 5 | Brian Maney | 131 | 2011-2017 | |
| 6 | Phil Goodman | 129 | 2013-2018 | |
| 7 | Jose Rios | 127 | 2007-2016 | |
| 8 | Guillermo de la Cruz | 125 | 2014-2019 | |
| 9 | Ahmed Harris# | 121 | 2021-2025 | |
| 9 | Jeremy Vander Meer | 121 | 2012-2016 | |
| 11 | Nick Randall | 119 | 2016-2021 | |
| 12 | Eric Albright | 118 | 2020-2023 | |
| 13 | Ralph Griffin | 117 | 2016-2020 | |
| 14 | Gerardo Matute# | 111 | 2021-2025 | |
| 15 | John Wendel | 110 | 2010-2015 | |
| 16 | Andrew Braden# | 107 | 2021-2024 | |
| 17 | Stuart Blankenship# | 105 | 2021-2024 | |
| 18 | Silvestro Cilento | 103 | 2012-2016 | |
| 18 | Tony Hernandez | 103 | 2000-2010 | |
| 20 | Riley Reid | 102 | 2017-2021 | |
| 21 | Jose Palacio | 101 | 2020-2023 | |
| 22 | Bobby Bierman | 100 | 2018-2023 | |
| 23 | Craig Treinen# | 98 | 2021-2024 | |
| 24 | Jonathan Aldama | 97 | 2007-2014 | |
| 24 | Keisuke Deshimaru | 97 | 2013-2020 | |
| 24 | Jaden Taylor | 97 | 2005-2013 | |
| 24 | Chris Wyzard# | 97 | 2018-2022 | |
| 28 | Sergio Hernandez | 96 | 2001-2013 | |
| 28 | Eric Lowman | 96 | 2011-2015 | |
| 30 | Aaron Aaron | 95 | 2015-2020 | |
| 30 | Chris Barrionuevo | 95 | 2004-2011 | |
| 30 | Kyle Yearwood# | 95 | 2021-2025 | |
| 33 | Albert Espinoza | 94 | 2017-2021 | |
| 34 | Mike Embrey | 93 | 2017-2021 | |
| 34 | Josh Graham | 93 | 2014-2018 | |
| 34 | Robby Matthews | 93 | 2011-2015 | |
| 34 | Mike Palmer | 93 | 2000-2010 | |
| 38 | Chris Mueller | 92 | 2020-2023 | |
| 38 | Enrique Perez | 92 | 2007-2023 | |
| 40 | Leo Medina | 91 | 2000-2009 | |
| 40 | Tokaji Sera | 91 | 2012-2016 | |
| 42 | Danny Justice | 90 | 2000-2010 | |
| 42 | Brian O'Connor | 90 | 2000-2006 | |
| 44 | Scott Clary# | 89 | 2022-2025 | |
| 44 | Emilio Salamanca | 89 | 2014-2018 | |
| 46 | Jamie Brown | 88 | 2016-2021 | |
| 47 | Jesus Barbiusa | 87 | 2014-2020 | |
| 47 | Casey Levy# | 87 | 2018-2025 | |
| 49 | Bill Campbell | 86 | 2012-2016 | |
| 49 | Devin Nisbet | 86 | 2001-2013 | |
| 51 | Luis Lozano | 85 | 2012-2019 | |
| 51 | Andres Torres | 85 | 2000-2008 | |
| 53 | Victor Avalos | 84 | 2014-2016 | |
| 53 | Gil Johnson | 84 | 2000-2010 | |
| 53 | Guo Liu | 84 | 2003-2010 | |
| 53 | Dan Presnell | 84 | 2019-2023 | |
| 53 | Dragutin Sujic | 84 | 2002-2013 | |
| 58 | Justin Bunt# | 82 | 2021-2023 | |
| 58 | Phil Solomon | 82 | 2011-2017 | |
| 58 | Joe St. Clair | 82 | 2006-2015 | |
| 61 | Will Barton | 81 | 2015-2018 | |
| 61 | Mike Carachure | 81 | 2010-2021 | |
| 61 | Mark DeSerio | 81 | 2015-2019 | |
| 61 | Salvador Vallego | 81 | 2015-2019 | |
| 65 | Chris Davies | 80 | 2018-2021 | |
| 65 | Brandon Elder | 80 | 2013-2017 | |
| 65 | Isaiah Gunter | 80 | 2008-2014 | |
| 65 | Santiago Melendez | 80 | 2011-2016 | |
| 69 | Kevin Barry | 78 | 2016-2020 | |
| 69 | Greg Flyer | 78 | 2000-2012 | |
| 69 | Robert Garcia | 78 | 2015-2020 | |
| 69 | Jack Hall | 78 | 2019-2022 | |
| 69 | Jesse Malone | 78 | 2004-2009 | |
| 69 | John Turner | 78 | 2020-2023 | |
| 75 | Josh Oakman# | 77 | 2018-2022 | |
| 75 | Chris Zuniga# | 77 | 2021-2025 | |
| 77 | Alex Moreno | 76 | 2009-2016 | |
| 78 | Kyle Chamberlin | 75 | 2013-2021 | |
| 78 | Justin Malloy | 75 | 2008-2015 | |
| 78 | Kurt Neal# | 75 | 2013-2025 | |
| 78 | Jesse Parker | 75 | 2000-2009 | |
| 78 | Jason Wittmann | 75 | 2018-2021 | |
| 83 | Danny Linares | 74 | 2011-2019 | |
| 83 | Tony Ramos | 74 | 2010-2014 | |
| 83 | Mike Revell# | 74 | 2018-2025 | |
| 86 | Danny Arroyo | 73 | 2020-2023 | |
| 86 | Jesse Bettinger | 73 | 2000-2010 | |
| 86 | Ryosuke Hosaka | 73 | 2000-2009 | |
| 86 | Kevin McGaha# | 73 | 2022-2025 | |
| 90 | Raul Cuartas | 72 | 2010-2013 | |
| 90 | Chase Goad | 72 | 2019-2021 | |
| 90 | Max Hercules# | 72 | 2020-2025 | |
| 90 | Ryan Iverson | 72 | 2001-2007 | |
| 90 | Bill Mitchell | 72 | 2013-2018 | |
| 90 | Daniel O'Mara | 72 | 2008-2014 | |
| 90 | Antonio Suarez | 72 | 2007-2016 | |
| 90 | Brian Webb | 72 | 2015-2021 | |
| 98 | John Loper | 71 | 2000-2009 | |
| 98 | Felix Marquez# | 71 | 2018-2024 | |
| 98 | Brendan Rees | 71 | 2001-2010 |
