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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Eric Burdine* | 30 | 2000-2017 | |
| 2 | Jonathan Luna | 24 | 2000-2011 | |
| 3 | Chad Landreth | 21 | 2001-2017 | |
| 4 | Joe Hart# | 19 | 2013-2024 | |
| 5 | Corey Gruver# | 18 | 2006-2024 | |
| 6 | Carlos Mendez# | 16 | 2011-2024 | |
| 6 | Alfredo Tiscareno# | 16 | 2010-2024 | |
| 8 | Brent Hansen# | 14 | 2020-2023 | |
| 8 | Elard Nijhuis | 14 | 2000-2009 | |
| 10 | Jay Helm# | 13 | 2015-2024 | |
| 10 | Antonio Higuera# | 13 | 2007-2024 | |
| 10 | Rodrigo Lemus# | 13 | 2013-2024 | |
| 13 | Heriberto Milan | 12 | 2007-2022 | |
| 13 | Sergio Penichet# | 12 | 2013-2024 | |
| 13 | Greg Sandlin# | 12 | 2009-2024 | |
| 13 | Kyle Ziegler | 12 | 2000-2011 | |
| 17 | Sean Bartol | 11 | 2000-2010 | |
| 17 | Nate Briceno# | 11 | 2015-2020 | |
| 17 | Zachary Christman# | 11 | 2014-2024 | |
| 17 | Jon Haynes# | 11 | 2014-2024 | |
| 17 | Cody Morosko | 11 | 2000-2010 | |
| 22 | Jonathan Allen# | 10 | 2016-2024 | |
| 22 | Miles Hale | 10 | 2000-2011 | |
| 22 | Jayden Nesmith# | 10 | 2012-2023 | |
| 22 | Bill Rauch | 10 | 2011-2023 | |
| 22 | Miguel Soto# | 10 | 2013-2024 | |
| 22 | Rodolfo Soto# | 10 | 2015-2024 | |
| 22 | Travis Thurber# | 10 | 2005-2024 | |
| 29 | Felipe Ayala# | 9 | 2013-2024 | |
| 29 | Ron Baumgardner | 9 | 2010-2019 | |
| 29 | Marty Capone# | 9 | 2019-2024 | |
| 29 | Xavier Cooper# | 9 | 2014-2024 | |
| 29 | Xiang-ling Fei* | 9 | 2000-2012 | |
| 29 | Victor Herrera | 9 | 2011-2018 | |
| 29 | Jack Ivory# | 9 | 2018-2024 | |
| 29 | Sukeaki Kato | 9 | 2001-2014 | |
| 29 | Tom Kitko | 9 | 2012-2023 | |
| 29 | Paul Ledford* | 9 | 2000-2013 | |
| 29 | Chris McLure | 9 | 2000-2010 | |
| 29 | Jose Moreno | 9 | 2000-2014 | |
| 29 | Ben O'Halloran# | 9 | 2016-2024 | |
| 29 | Brian Rohde | 9 | 2009-2020 | |
| 29 | Luke Scrimger# | 9 | 2019-2024 | |
| 29 | Chad Stokes | 9 | 2006-2017 | |
| 45 | Josh Canas# | 8 | 2023-2024 | |
| 45 | Gordie Clifford# | 8 | 2013-2024 | |
| 45 | Justin Jemison# | 8 | 2019-2024 | |
| 45 | Du-sung Moon | 8 | 2002-2015 | |
| 45 | Andres Moran | 8 | 2011-2022 | |
| 45 | David Nations | 8 | 2000-2008 | |
| 45 | Adrian Radecki | 8 | 2012-2019 | |
| 45 | Ray Rorie# | 8 | 2016-2024 | |
| 45 | Sean Stevens# | 8 | 2023-2024 | |
| 45 | Bill Vasquez | 8 | 2000-2012 | |
| 45 | Andy Weatherholt# | 8 | 2021-2024 | |
| 56 | Casey Abbott# | 7 | 2009-2024 | |
| 56 | Vance Adams | 7 | 2000-2013 | |
| 56 | Miguel Berrios# | 7 | 2018-2024 | |
| 56 | Francisco Camacho | 7 | 2000-2013 | |
| 56 | Brian Chambliss | 7 | 2000-2014 | |
| 56 | Jordan Clarke | 7 | 2004-2023 | |
| 56 | Adam D'Alberto# | 7 | 2016-2024 | |
| 56 | Geremia Farinelli | 7 | 2000-2014 | |
| 56 | Justin Fielding | 7 | 2000-2013 | |
| 56 | Ryan Flamino# | 7 | 2020-2024 | |
| 56 | Bill Flowers# | 7 | 2011-2024 | |
| 56 | Tyrone Hairston | 7 | 2002-2013 | |
| 56 | Byung-sik Lee | 7 | 2006-2014 | |
| 56 | Lee Morgan# | 7 | 2019-2024 | |
| 56 | Mike Nave | 7 | 2009-2017 | |
| 56 | Iliana Preciado | 7 | 2000-2009 | |
| 56 | Logan Stone | 7 | 2010-2022 | |
| 56 | Kory Tourville# | 7 | 2014-2024 | |
| 74 | Sam Campos# | 6 | 2020-2023 | |
| 74 | Seth Carey | 6 | 2004-2016 | |
| 74 | Oreste Comollo | 6 | 2001-2014 | |
| 74 | Josh Cowels# | 6 | 2021-2024 | |
| 74 | Chris Cowen | 6 | 2006-2019 | |
| 74 | Bobby Dodd | 6 | 2005-2016 | |
| 74 | David Edgemon# | 6 | 2021-2024 | |
| 74 | Albert Fabian# | 6 | 2014-2024 | |
| 74 | Chris Fitzsimmons# | 6 | 2015-2023 | |
| 74 | Noah George | 6 | 2005-2017 | |
| 74 | Rusty Hays | 6 | 2000-2009 | |
| 74 | Ryan Henry# | 6 | 2022-2024 | |
| 74 | Bobby Moreno | 6 | 2005-2014 | |
| 74 | Pat Payne | 6 | 2009-2023 | |
| 74 | Javier Ramos | 6 | 2013-2024 | |
| 74 | Jonathan Roten# | 6 | 2014-2022 | |
| 74 | Willie Sanchez | 6 | 2000-2011 | |
| 74 | Matt Schmid# | 6 | 2013-2023 | |
| 92 | Israel Alicea | 5 | 2004-2009 | |
| 92 | Jose Alvarado | 5 | 2006-2016 | |
| 92 | William Arredondo | 5 | 2000-2012 | |
| 92 | Blake Barber | 5 | 2000-2007 | |
| 92 | Josh Becker# | 5 | 2020-2024 | |
| 92 | Omar Cons# | 5 | 2023-2024 | |
| 92 | Bradley Cooper | 5 | 2000-2007 | |
| 92 | Adam Farmer | 5 | 2000-2009 | |
| 92 | Ben Farnell | 5 | 2003-2012 |
