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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Omar Pena | 378 | 2000-2011 | |
| 2 | Paul Pittman# | 362 | 2013-2024 | |
| 3 | Zach Swint | 304 | 2001-2016 | |
| 4 | Ken Bennett | 222 | 2000-2009 | |
| 5 | Bobby Tapia# | 217 | 2008-2024 | |
| 6 | Austin Compton# | 208 | 2015-2024 | |
| 7 | Luis Vasquez | 202 | 2006-2016 | |
| 8 | Mike Plocher | 199 | 2000-2009 | |
| 9 | Matthew Little# | 196 | 2018-2024 | |
| 10 | Carlos Martinez | 189 | 2003-2016 | |
| 11 | Alberto Ojeda* | 176 | 2002-2016 | |
| 12 | Ryan Forsythe# | 171 | 2018-2024 | |
| 13 | Gong-sun Thum | 164 | 2011-2020 | |
| 14 | Bob Johnson | 159 | 2000-2012 | |
| 15 | Juan Membreno | 157 | 2006-2020 | |
| 16 | Rocky Hawke# | 153 | 2018-2024 | |
| 16 | Julio Rojo | 153 | 2000-2008 | |
| 18 | Fernando Serrano | 120 | 2010-2020 | |
| 19 | Ton Ariëns# | 119 | 2021-2024 | |
| 19 | Roberto Gonzalez | 119 | 2000-2003 | |
| 21 | Ivan Galvan | 115 | 2010-2019 | |
| 22 | Chris Stover | 111 | 2016-2020 | |
| 23 | Tae-hyeon Hahn | 110 | 2009-2017 | |
| 24 | Travis Collier | 104 | 2010-2022 | |
| 25 | Danny Greeman | 103 | 2004-2010 | |
| 26 | Steve Fisher | 99 | 2010-2018 | |
| 27 | Lorenzo Novo | 98 | 2000-2013 | |
| 27 | Kevin Tibbens | 98 | 2000-2015 | |
| 29 | Marco Fermin | 97 | 2000-2008 | |
| 30 | Jason Saunders# | 95 | 2018-2023 | |
| 31 | Jason Morrow | 91 | 2001-2010 | |
| 32 | Eric Brewer# | 84 | 2015-2024 | |
| 32 | Dan James | 84 | 2015-2020 | |
| 32 | Josh Law# | 84 | 2017-2024 | |
| 35 | Willie Arellanes | 83 | 2000-2009 | |
| 35 | Xavier Jackson | 83 | 2004-2011 | |
| 37 | Manny Perez | 82 | 2000-2006 | |
| 38 | Dan Taylor | 81 | 2004-2017 | |
| 39 | Nick Seago# | 77 | 2018-2024 | |
| 40 | Jose Torres | 68 | 2000-2006 | |
| 41 | Brian Roseman# | 67 | 2023-2024 | |
| 41 | Mike Townsend# | 67 | 2018-2024 | |
| 43 | Miguel Meza | 64 | 2009-2020 | |
| 43 | Bobby Oliver# | 64 | 2019-2021 | |
| 45 | Carlos Martinez | 62 | 2008-2015 | |
| 46 | Jeremy Alfano# | 61 | 2020-2022 | |
| 47 | Jody Garner | 60 | 2001-2012 | |
| 47 | Cipta Lubis | 60 | 2007-2012 | |
| 47 | Elijah Moody# | 60 | 2021-2022 | |
| 50 | Nate Bacle# | 59 | 2015-2021 | |
| 50 | Charlie Waters | 59 | 2001-2012 | |
| 52 | Paul McCarthy# | 58 | 2018-2024 | |
| 52 | Victor Mendez# | 58 | 2021-2024 | |
| 54 | Dane Howell | 55 | 2002-2012 | |
| 54 | Isaiah Stanley | 55 | 2001-2012 | |
| 56 | Walt Lepore | 54 | 2014-2020 | |
| 56 | Stephen Stewart | 54 | 2000-2007 | |
| 58 | T.J. Donovan# | 52 | 2020-2024 | |
| 58 | Dave Jones | 52 | 2017-2022 | |
| 60 | Heath Sherlock# | 50 | 2021-2024 | |
| 61 | Norman Moyers | 49 | 2000-2007 | |
| 62 | Travis LeBrun | 48 | 2011-2016 | |
| 63 | George Dashiell | 47 | 2000-2009 | |
| 64 | Brian Byrd# | 43 | 2014-2023 | |
| 64 | Chris Denney# | 43 | 2018-2021 | |
| 64 | Kyle Fitzpatrick | 43 | 2009-2015 | |
| 64 | Eric Hicks# | 43 | 2022-2024 | |
| 64 | Dan Powell | 43 | 2004-2012 | |
| 69 | Ricky Ordonez# | 42 | 2017-2024 | |
| 69 | Steve Post# | 42 | 2022-2024 | |
| 71 | Gary Draeger# | 41 | 2016-2024 | |
| 72 | Jose Lazaro# | 39 | 2022-2024 | |
| 72 | Severo Salcido# | 39 | 2013-2023 | |
| 74 | Phil Cook | 38 | 2006-2017 | |
| 74 | Danny Morales | 38 | 2010-2015 | |
| 74 | Chris Pargeon | 38 | 2006-2015 | |
| 77 | Steve Pate | 37 | 2000-2009 | |
| 78 | Keagan Deming# | 36 | 2019-2022 | |
| 78 | Jim Johnston | 36 | 2006-2013 | |
| 80 | Pat Albury | 35 | 2014-2016 | |
| 80 | Tony Arteaga | 35 | 2016-2021 | |
| 82 | Alex Natera# | 34 | 2021-2024 | |
| 82 | Bert Vega | 34 | 2000-2001 | |
| 84 | John Gadsden# | 33 | 2022-2024 | |
| 84 | Jasper Sloan | 33 | 2002-2011 | |
| 86 | Tiberio Donelli | 32 | 2001-2011 | |
| 87 | Travis Baynes | 31 | 2000-2005 | |
| 87 | Jonathan Cunningham# | 31 | 2021-2024 | |
| 87 | Aaron Davenport# | 31 | 2023-2024 | |
| 87 | Jake Densberger# | 31 | 2017-2022 | |
| 91 | Chris Goldsmith# | 29 | 2022-2023 | |
| 92 | Juan Garcia# | 28 | 2010-2023 | |
| 92 | Roberto Perez# | 28 | 2017-2023 | |
| 92 | Hua Pian | 28 | 2000-2003 | |
| 95 | Ryan Young | 27 | 2011-2017 | |
| 96 | Brock Farlow | 26 | 2017-2019 | |
| 96 | Kevin Schneider# | 26 | 2023-2024 | |
| 96 | Josh Tschinkel | 26 | 2003-2010 | |
| 99 | Jaden Gregory | 25 | 2007-2017 | |
| 99 | Earl Lindsey | 25 | 2007-2013 |
