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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Antonio Higuera# | 436 | 2007-2023 | |
| 2 | Corey Gruver# | 346 | 2006-2024 | |
| 3 | Eric Burdine* | 333 | 2000-2017 | |
| 3 | Geremia Farinelli | 333 | 2000-2014 | |
| 5 | Heriberto Milan | 319 | 2007-2022 | |
| 6 | Greg Sandlin# | 318 | 2009-2024 | |
| 7 | Jordan Clarke | 314 | 2004-2023 | |
| 8 | Barry McLamb# | 309 | 2013-2023 | |
| 9 | Chad Landreth | 306 | 2001-2017 | |
| 10 | Jonathan Luna | 287 | 2000-2011 | |
| 11 | David Nations | 283 | 2000-2008 | |
| 12 | Vance Adams | 281 | 2000-2013 | |
| 13 | J.R. Mitchell# | 279 | 2013-2024 | |
| 14 | Xiang-ling Fei* | 273 | 2000-2012 | |
| 15 | Tony Lopez | 265 | 2013-2021 | |
| 16 | William Arredondo | 263 | 2000-2012 | |
| 17 | Miles Hale | 261 | 2000-2011 | |
| 18 | Kyle Ziegler | 259 | 2000-2011 | |
| 19 | Jose Alvarado | 257 | 2006-2016 | |
| 20 | Brian Chambliss | 252 | 2000-2014 | |
| 21 | Chris McLure | 250 | 2000-2010 | |
| 22 | Tyrone Hairston | 248 | 2002-2013 | |
| 23 | Casey Abbott# | 243 | 2009-2024 | |
| 24 | Brian Rohde | 239 | 2009-2020 | |
| 25 | Edwin Gutierrez | 235 | 2000-2010 | |
| 25 | Carlos Mendez# | 235 | 2011-2024 | |
| 27 | Alfredo Tiscareno# | 234 | 2010-2024 | |
| 28 | Albert Fabian# | 233 | 2014-2024 | |
| 29 | Sean Bartol | 232 | 2000-2010 | |
| 30 | Paul Ledford* | 230 | 2000-2013 | |
| 31 | Brian Prince# | 229 | 2011-2024 | |
| 32 | Russ Allen | 228 | 2000-2012 | |
| 32 | Jose Moreno | 228 | 2000-2014 | |
| 34 | Du-sung Moon | 227 | 2002-2015 | |
| 35 | John Way# | 226 | 2016-2024 | |
| 36 | Gates Callaghan | 224 | 2004-2014 | |
| 37 | Tom Kitko# | 223 | 2012-2023 | |
| 38 | Pat Gonzalez | 222 | 2000-2013 | |
| 38 | Andy Shoemaker# | 222 | 2012-2023 | |
| 40 | Zachary Christman# | 221 | 2014-2024 | |
| 41 | Tony Figueroa | 219 | 2014-2021 | |
| 42 | Bobby Dodd | 217 | 2005-2016 | |
| 42 | Nick Mathiesen | 217 | 2000-2010 | |
| 44 | Seth Carey | 216 | 2004-2016 | |
| 44 | Jay Helm# | 216 | 2015-2024 | |
| 46 | Iliana Preciado | 212 | 2000-2009 | |
| 47 | Hiromi Fukuda | 210 | 2006-2018 | |
| 48 | Cody Morosko | 207 | 2000-2010 | |
| 49 | John Froerer# | 206 | 2015-2024 | |
| 50 | Eric Angelone | 205 | 2004-2013 | |
| 51 | Hector Ruiz | 203 | 2001-2013 | |
| 51 | Bill Vasquez | 203 | 2000-2012 | |
| 53 | Nick Lawson | 199 | 2002-2017 | |
| 54 | Octavio Ruiz | 198 | 2000-2011 | |
| 55 | Felipe Gonzalez | 197 | 2011-2020 | |
| 56 | Andres Moran# | 196 | 2011-2022 | |
| 57 | Tony Marcano | 195 | 2000-2011 | |
| 58 | Rogelio Aburto | 192 | 2009-2020 | |
| 58 | Winston Caballero# | 192 | 2015-2024 | |
| 60 | Tommy Bressette | 188 | 2000-2009 | |
| 61 | Jeremy Gray# | 187 | 2013-2024 | |
| 61 | Jeremy Hewes | 187 | 2010-2022 | |
| 63 | Chris Kuperman | 186 | 2002-2012 | |
| 63 | Jorge Lopez | 186 | 2004-2013 | |
| 65 | Felipe Ayala# | 185 | 2013-2024 | |
| 66 | Jon Haynes# | 184 | 2014-2024 | |
| 66 | Lorenzo Villarreal# | 184 | 2014-2024 | |
| 68 | Seth Dann | 183 | 2002-2013 | |
| 68 | Ching Ding | 183 | 2000-2009 | |
| 68 | Noah George | 183 | 2005-2017 | |
| 68 | Jeff Glissman | 183 | 2000-2010 | |
| 72 | Adrian Huffine# | 182 | 2015-2024 | |
| 73 | Sukeaki Kato | 179 | 2001-2014 | |
| 73 | Dave Shevlin# | 179 | 2013-2024 | |
| 73 | Rodolfo Soto# | 179 | 2015-2024 | |
| 76 | Bill Flowers# | 177 | 2011-2024 | |
| 76 | Sergio Penichet# | 177 | 2013-2024 | |
| 78 | Chris Harris | 176 | 2007-2020 | |
| 79 | Julio Melendez | 175 | 2000-2012 | |
| 79 | Bill Rauch# | 175 | 2011-2023 | |
| 81 | Jonathan Allen# | 173 | 2016-2024 | |
| 81 | Miguel Leon# | 173 | 2017-2024 | |
| 83 | Alex Dopico | 172 | 2000-2009 | |
| 83 | Jason Strobel# | 172 | 2014-2024 | |
| 85 | Alex Alvarez | 171 | 2010-2019 | |
| 86 | Xavier Cooper# | 170 | 2014-2024 | |
| 86 | Jeff Rochefort | 170 | 2009-2019 | |
| 86 | Kyle Rodriguez# | 170 | 2014-2023 | |
| 89 | Jonathan Gonzales | 169 | 2012-2023 | |
| 89 | Yosaburo Kanda | 169 | 2013-2022 | |
| 89 | Tim Ward | 169 | 2000-2009 | |
| 92 | Rodrigo Lemus# | 168 | 2013-2024 | |
| 92 | Elard Nijhuis | 168 | 2000-2009 | |
| 94 | Byung-sik Lee | 167 | 2006-2014 | |
| 94 | Chris Mattison | 167 | 2012-2019 | |
| 94 | Travis Thurber# | 167 | 2005-2023 | |
| 94 | Keith Young | 167 | 2000-2007 | |
| 98 | Ryan Heyer# | 166 | 2017-2024 | |
| 98 | Pat Hovhannisian# | 166 | 2014-2024 | |
| 98 | Chris Shifflett | 166 | 2004-2014 |
