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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Antonio Higuera# | 395 | 2007-2022 | |
| 2 | Eric Burdine | 333 | 2000-2017 | |
| 2 | Geremia Farinelli | 333 | 2000-2014 | |
| 4 | Heriberto Milan# | 319 | 2007-2022 | |
| 5 | Jordan Clarke# | 312 | 2004-2022 | |
| 6 | Corey Gruver# | 310 | 2006-2022 | |
| 7 | Chad Landreth | 306 | 2001-2017 | |
| 8 | Jonathan Luna | 287 | 2000-2011 | |
| 9 | Greg Sandlin# | 286 | 2009-2022 | |
| 10 | David Nations | 283 | 2000-2008 | |
| 11 | Vance Adams | 281 | 2000-2013 | |
| 12 | Xiang-ling Fei* | 273 | 2000-2012 | |
| 13 | Tony Lopez# | 265 | 2013-2021 | |
| 14 | William Arredondo | 263 | 2000-2012 | |
| 14 | Barry McLamb# | 263 | 2013-2022 | |
| 16 | Miles Hale | 261 | 2000-2011 | |
| 17 | Kyle Ziegler | 259 | 2000-2011 | |
| 18 | Jose Alvarado | 257 | 2006-2016 | |
| 19 | Brian Chambliss | 252 | 2000-2014 | |
| 20 | Chris McLure | 250 | 2000-2010 | |
| 21 | Tyrone Hairston | 248 | 2002-2013 | |
| 22 | Brian Rohde | 239 | 2009-2020 | |
| 23 | J.R. Mitchell# | 237 | 2013-2022 | |
| 24 | Edwin Gutierrez | 235 | 2000-2010 | |
| 25 | Sean Bartol | 232 | 2000-2010 | |
| 26 | Paul Ledford* | 230 | 2000-2013 | |
| 27 | Russ Allen | 228 | 2000-2012 | |
| 27 | Jose Moreno | 228 | 2000-2014 | |
| 29 | Du-sung Moon | 227 | 2002-2015 | |
| 30 | Gates Callaghan | 224 | 2004-2014 | |
| 31 | Tom Kitko# | 223 | 2012-2022 | |
| 32 | Pat Gonzalez | 222 | 2000-2013 | |
| 33 | Tony Figueroa# | 219 | 2014-2021 | |
| 34 | Casey Abbott# | 218 | 2009-2022 | |
| 35 | Bobby Dodd | 217 | 2005-2016 | |
| 35 | Nick Mathiesen | 217 | 2000-2010 | |
| 37 | Seth Carey | 216 | 2004-2016 | |
| 38 | Iliana Preciado | 212 | 2000-2009 | |
| 39 | Hiromi Fukuda | 210 | 2006-2018 | |
| 40 | Andy Shoemaker# | 209 | 2012-2022 | |
| 41 | Cody Morosko | 207 | 2000-2010 | |
| 41 | Brian Prince# | 207 | 2011-2022 | |
| 43 | Albert Fabian# | 206 | 2014-2022 | |
| 44 | Eric Angelone | 205 | 2004-2013 | |
| 45 | Hector Ruiz | 203 | 2001-2013 | |
| 45 | Bill Vasquez | 203 | 2000-2012 | |
| 47 | Carlos Mendez# | 202 | 2011-2022 | |
| 48 | Alfredo Tiscareno# | 201 | 2010-2022 | |
| 49 | Nick Lawson | 199 | 2002-2017 | |
| 50 | Octavio Ruiz | 198 | 2000-2011 | |
| 51 | Felipe Gonzalez# | 197 | 2011-2020 | |
| 52 | Andres Moran# | 196 | 2011-2022 | |
| 53 | Tony Marcano | 195 | 2000-2011 | |
| 54 | Rogelio Aburto | 192 | 2009-2020 | |
| 55 | Tommy Bressette | 188 | 2000-2009 | |
| 56 | Zachary Christman# | 187 | 2014-2022 | |
| 56 | Jeremy Hewes# | 187 | 2010-2022 | |
| 58 | Chris Kuperman | 186 | 2002-2012 | |
| 58 | Jorge Lopez | 186 | 2004-2013 | |
| 60 | Seth Dann | 183 | 2002-2013 | |
| 60 | Ching Ding | 183 | 2000-2009 | |
| 60 | Noah George | 183 | 2005-2017 | |
| 60 | Jeff Glissman | 183 | 2000-2010 | |
| 64 | John Way# | 181 | 2016-2022 | |
| 65 | Sukeaki Kato | 179 | 2001-2014 | |
| 66 | Chris Harris | 176 | 2007-2020 | |
| 67 | Jay Helm# | 175 | 2015-2022 | |
| 67 | Julio Melendez | 175 | 2000-2012 | |
| 69 | Alex Dopico | 172 | 2000-2009 | |
| 70 | Alex Alvarez# | 171 | 2010-2019 | |
| 71 | Jeff Rochefort# | 170 | 2009-2019 | |
| 72 | Yosaburo Kanda# | 169 | 2013-2022 | |
| 72 | Tim Ward | 169 | 2000-2009 | |
| 74 | John Froerer# | 168 | 2015-2022 | |
| 74 | Elard Nijhuis | 168 | 2000-2009 | |
| 76 | Byung-sik Lee | 167 | 2006-2014 | |
| 76 | Chris Mattison# | 167 | 2012-2019 | |
| 76 | Keith Young | 167 | 2000-2007 | |
| 79 | Bill Rauch# | 166 | 2011-2022 | |
| 79 | Chris Shifflett | 166 | 2004-2014 | |
| 79 | Nate Simons | 166 | 2003-2012 | |
| 82 | Willie Sanchez | 164 | 2000-2011 | |
| 82 | Ruben Ulloa | 164 | 2000-2008 | |
| 84 | Tomas Adon | 163 | 2004-2018 | |
| 84 | David Jacquez | 163 | 2000-2011 | |
| 84 | Kyle Rodriguez# | 163 | 2014-2022 | |
| 87 | Ryan DeVault | 162 | 2007-2015 | |
| 87 | Danny Freeman | 162 | 2001-2010 | |
| 87 | Matthew Thomas# | 162 | 2013-2022 | |
| 87 | Travis Thurber# | 162 | 2005-2021 | |
| 87 | Lorenzo Villarreal# | 162 | 2014-2022 | |
| 92 | Winston Caballero# | 161 | 2015-2022 | |
| 92 | Jonathan Gonzales# | 161 | 2012-2022 | |
| 94 | Jon Haynes# | 160 | 2014-2022 | |
| 94 | Ray Stanberry | 160 | 2000-2007 | |
| 96 | Adrian Huffine# | 159 | 2015-2022 | |
| 97 | Javy Mendoza | 158 | 2000-2010 | |
| 97 | Bobby Moreno | 158 | 2005-2014 | |
| 97 | Travis Salopek# | 158 | 2014-2022 | |
| 100 | Rusty Hays | 157 | 2000-2009 |
