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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Pedro Rangel# | 24 | 2021 | |
| 2 | Dave Acosta# | 10 | 2021 | |
| 3 | Jeremy Callis# | 8 | 2021 | |
| 4 | Todd Korn# | 7 | 2021 | |
| 4 | Jacob Tubman# | 7 | 2021 | |
| 4 | Ben McCabe# | 7 | 2021 | |
| 7 | Jim Henkemeyer# | 6 | 2021 | |
| 7 | Chris Stanifer# | 6 | 2021 | |
| 7 | Joe Robinson# | 6 | 2021 | |
| 10 | Nick Sumney# | 5 | 2021 | |
| 10 | Paul Nicolopoulos# | 5 | 2021 | |
| 10 | Billy Oliveros# | 5 | 2021 | |
| 10 | Ben Porter# | 5 | 2021 | |
| 10 | Armando Cuevas# | 5 | 2021 | |
| 15 | Jason Eaton# | 4 | 2021 | |
| 15 | Alfredo Cruz# | 4 | 2021 | |
| 15 | Charlie Harrison# | 4 | 2021 | |
| 15 | Bill Dent# | 4 | 2021 | |
| 19 | Jay McBurney# | 3 | 2021 | |
| 19 | Danny Molina# | 3 | 2021 | |
| 21 | Pat Kirchner# | 2 | 2021 | |
| 21 | Adam McCumiskey# | 2 | 2021 | |
| 21 | Manny Placencia# | 2 | 2021 | |
| 21 | Roberto Castruita# | 2 | 2021 | |
| 25 | Greg Biever# | 1 | 2021 |
