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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Fei-hsien Liu# | 48 | 2021 | |
| 2 | Justin Jirkovsky# | 43 | 2021 | |
| 3 | John Gadsden# | 37 | 2021 | |
| 4 | Josh Kelly# | 36 | 2021 | |
| 5 | Jose Sanchez# | 33 | 2021 | |
| 6 | Kevin Schneider# | 32 | 2021 | |
| 7 | Francisco O'Brien# | 31 | 2021 | |
| 7 | David Byerly# | 31 | 2021 | |
| 9 | Mike Jamin# | 30 | 2021 | |
| 10 | Orlando de Jesus# | 25 | 2021 | |
| 11 | Nick Kujawa# | 24 | 2021 | |
| 12 | Jack Ficca# | 23 | 2021 | |
| 13 | Jaime Tate# | 21 | 2021 | |
| 13 | Jim Henkemeyer# | 21 | 2021 | |
| 13 | Dale Coffey# | 21 | 2021 | |
| 16 | Dave Moe# | 20 | 2021 | |
| 17 | Eduardo Acosta# | 19 | 2021 | |
| 17 | Josh Alcorn# | 19 | 2021 | |
| 19 | Jose Espinoza# | 15 | 2021 | |
| 20 | Billy Groesbeck# | 10 | 2021 |
